酰基辅酶 A β-氧化在脑代谢和神经退行性疾病中的作用。
The Role of Acyl-CoA β-Oxidation in Brain Metabolism and Neurodegenerative Diseases.
机构信息
Department of Biochemistry, Faculty of Medicine, Medical University of Gdansk, 80-211 Gdansk, Poland.
Institute of Nursing and Medical Rescue, State University of Applied Sciences in Koszalin, 75-582 Koszalin, Poland.
出版信息
Int J Mol Sci. 2023 Sep 12;24(18):13977. doi: 10.3390/ijms241813977.
Abstract
This review highlights the complex role of fatty acid β-oxidation in brain metabolism. It demonstrates the fundamental importance of fatty acid degradation as a fuel in energy balance and as an essential component in lipid homeostasis, brain aging, and neurodegenerative disorders.
摘要
本篇综述强调了脂肪酸β-氧化在大脑代谢中的复杂作用。它展示了脂肪酸降解作为能量平衡中的燃料，以及作为脂质动态平衡、大脑衰老和神经退行性疾病的重要组成部分的基本重要性。
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