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酰基辅酶 A β-氧化在脑代谢和神经退行性疾病中的作用。

The Role of Acyl-CoA β-Oxidation in Brain Metabolism and Neurodegenerative Diseases.

机构信息

Department of Biochemistry, Faculty of Medicine, Medical University of Gdansk, 80-211 Gdansk, Poland.

Institute of Nursing and Medical Rescue, State University of Applied Sciences in Koszalin, 75-582 Koszalin, Poland.

出版信息

Int J Mol Sci. 2023 Sep 12;24(18):13977. doi: 10.3390/ijms241813977.

DOI:10.3390/ijms241813977
PMID:37762279
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10531288/
Abstract

This review highlights the complex role of fatty acid β-oxidation in brain metabolism. It demonstrates the fundamental importance of fatty acid degradation as a fuel in energy balance and as an essential component in lipid homeostasis, brain aging, and neurodegenerative disorders.

摘要

本篇综述强调了脂肪酸β-氧化在大脑代谢中的复杂作用。它展示了脂肪酸降解作为能量平衡中的燃料，以及作为脂质动态平衡、大脑衰老和神经退行性疾病的重要组成部分的基本重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16af/10531288/0cd87701adef/ijms-24-13977-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16af/10531288/a39887b4635d/ijms-24-13977-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16af/10531288/ee9568835507/ijms-24-13977-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16af/10531288/7ad3a6f097b3/ijms-24-13977-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16af/10531288/0cd87701adef/ijms-24-13977-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16af/10531288/a39887b4635d/ijms-24-13977-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16af/10531288/c986df527ecf/ijms-24-13977-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16af/10531288/ee9568835507/ijms-24-13977-g003.jpg
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