Mou Jiayou, Wang Chenxi, Zhao Hongyi, Xiong Chuwei, Ren Yong, Wang Jing, Jiang Dan, Zheng Zansheng
Research Group for Fluids and Thermal Engineering, University of Nottingham Ningbo China, Ningbo 315100, China.
Department of Mechanical, Materials and Manufacturing Engineering, University of Nottingham Ningbo China, Ningbo 315100, China.
Micromachines (Basel). 2023 Sep 6;14(9):1741. doi: 10.3390/mi14091741.
Nickel sesquioxide (NiO) nanoparticles were synthesized using centrifugal microfluidics in the present study. The obtained nanoparticles were characterized using SEM to investigate their morphology and microstructure, and XRD was employed to analyze their purity. The nanoparticle size data were measured and analyzed using ImageJ (v1.8.0) software. The flow process and mixing procedure were monitored through computational fluid dynamics simulation. Among the synthesized NiO nanoparticles, those obtained at the rotation speed of 1000 rpm for 10 min with angular acceleration of 4.2 rad/s showed the best performance in terms of high purity, complete shape and microstructure, small diameter, and narrow diameter distribution. The experimental results demonstrate that the rotation speed of the microfluidic chip and reaction time contribute to a decrease in particle diameter and a narrower diameter distribution range. In contrast, an increase in acceleration of the rotation speed leads to an expanded nanoparticle size range and, thus, a wider distribution. These findings contribute to a comprehensive understanding of the effects exerted by various factors in centrifugal microfluidics and will provide new insights into nanoparticle synthesis using centrifugal microfluidic technology.
在本研究中，使用离心微流控技术合成了三氧化二镍（NiO）纳米颗粒。利用扫描电子显微镜（SEM）对所得纳米颗粒进行表征，以研究其形态和微观结构，并采用X射线衍射（XRD）分析其纯度。使用ImageJ（v1.8.0）软件测量和分析纳米颗粒尺寸数据。通过计算流体动力学模拟监测流动过程和混合过程。在合成的NiO纳米颗粒中，那些在1000 rpm的转速下旋转10分钟且角加速度为4.2 rad/s时获得的纳米颗粒，在高纯度、完整的形状和微观结构、小直径以及窄直径分布方面表现出最佳性能。实验结果表明，微流控芯片的转速和反应时间有助于减小粒径并使直径分布范围变窄。相反，转速加速度的增加会导致纳米颗粒尺寸范围扩大，从而分布更宽。这些发现有助于全面理解离心微流控中各种因素所产生的影响，并将为利用离心微流控技术合成纳米颗粒提供新的见解。
