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基于超导生物传感器的神经肌肉磁场测量

Neuromuscular Magnetic Field Measurement Based on Superconducting Bio-Sensors.

作者信息

Zhang Zhidan, He Anran, Xu Zihan, Yang Kun, Kong Xiangyan

机构信息

The Institute for Future Wireless Research (iFWR), Ningbo University, Ningbo 315211, China.

The Faculty of Electrical Engineering and Computer Science, Ningbo University, Ningbo 315211, China.

出版信息

Micromachines (Basel). 2023 Sep 15;14(9):1768. doi: 10.3390/mi14091768.

Abstract

These years, disease-causing and disabling diseases have caused great concern. Neurological musculoskeletal disorders are diverse and affect people of a wide range of ages. And the lack of comprehensive diagnostic methods places a huge burden on healthcare systems and social economies. In this paper, the current status of clinical research on neuromuscular diseases is introduced, and the advantages of magnetic field measurement compared with clinical diagnostic methods are illustrated. A comprehensive description of the related technology of superconducting quantum interference devices (SQUIDs), magnetic field detection noise suppression scheme, the development trend of the sensor detection system, and the application and model establishment of the neuromuscular magnetic field is also given in this paper. The current research and development trends worldwide are compared simultaneously, and finally the conclusions and outlook are put forward. Based on the description of the existing literature and the ideas of other researchers, the next development trends and my own research ideas are presented in this paper, that is, starting from the establishment of a neuromuscular model, combining medical and industrial work, designing a sensor system that meets clinical needs, and laying the foundation for the clinical application of a bio-magnetic system. This review promotes a combination between medicine and industry, and guides researchers on considering the challenges of sensor development in terms of clinical needs. In addition, in this paper, the development trends are described, including the establishment of the model, the clinical demand for sensors, and the challenges of system development so as to give certain guidance to researchers.

摘要

近年来,致病和致残性疾病备受关注。神经肌肉骨骼疾病种类繁多,影响着广泛年龄段的人群。而缺乏全面的诊断方法给医疗系统和社会经济带来了巨大负担。本文介绍了神经肌肉疾病的临床研究现状,并阐述了磁场测量相对于临床诊断方法的优势。本文还对超导量子干涉器件(SQUIDs)的相关技术、磁场检测噪声抑制方案、传感器检测系统的发展趋势以及神经肌肉磁场的应用和模型建立进行了全面描述。同时比较了全球当前的研究和发展趋势,最后提出了结论与展望。基于现有文献的描述和其他研究者的思路,本文提出了未来的发展趋势和本人的研究思路,即从建立神经肌肉模型入手,结合医学和工业工作,设计出满足临床需求的传感器系统,为生物磁系统的临床应用奠定基础。这篇综述促进了医学与工业的结合,并引导研究人员从临床需求的角度考虑传感器开发面临的挑战。此外,本文还描述了发展趋势,包括模型的建立、传感器的临床需求以及系统开发面临的挑战,从而为研究人员提供一定的指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60f3/10535156/081286613222/micromachines-14-01768-g001.jpg

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