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用于皮特斯拉磁肌图的超高灵敏磁电传感系统。

Ultrasensitive Magnetoelectric Sensing System for Pico-Tesla MagnetoMyoGraphy.

出版信息

IEEE Trans Biomed Circuits Syst. 2020 Oct;14(5):971-984. doi: 10.1109/TBCAS.2020.2998290. Epub 2020 May 28.

DOI:10.1109/TBCAS.2020.2998290
PMID:32746340
Abstract

Magnetomyography (MMG) with superconducting quantum interference devices (SQUIDs) enabled the measurement of very weak magnetic fields (femto to pico Tesla) generated from the human skeletal muscles during contraction. However, SQUIDs are bulky, costly, and require working in a temperature-controlled environment, limiting wide-spread clinical use. We introduce a low-profile magnetoelectric (ME) sensor with analog frontend circuitry that has sensitivity to measure pico-Tesla MMG signals at room temperature. It comprises magnetostrictive and piezoelectric materials, FeCoSiB/AlN. Accurate device modelling and simulation are presented to predict device fabrication process comprehensively using the finite element method (FEM) in COMSOL Multiphysics. The fabricated ME chip with its readout circuit was characterized under a dynamic geomagnetic field cancellation technique. The ME sensor experiment validate a very linear response with high sensitivities of up to 378 V/T driven at a resonance frequency of f = 7.76 kHz. Measurements show the sensor limit of detections of down to 175 pT/√Hz at resonance, which is in the range of MMG signals. Such a small-scale sensor has the potential to monitor chronic movement disorders and improve the end-user acceptance of human-machine interfaces.

摘要

超导量子干涉器件 (SQUID) 的肌电图 (MMG) 可测量人类骨骼肌收缩时产生的非常微弱的磁场(飞特斯拉到皮特斯拉)。然而,SQUID 体积庞大、成本高昂,且需要在温控环境中工作,限制了其广泛的临床应用。我们引入了一种具有模拟前端电路的低剖面磁电 (ME) 传感器,具有测量皮特斯拉 MMG 信号的灵敏度,可以在室温下工作。它由磁致伸缩和压电材料 FeCoSiB/AlN 组成。使用 COMSOL Multiphysics 中的有限元法 (FEM) 对器件进行了精确的建模和模拟,以全面预测器件制造工艺。在动态地磁场消除技术下,对带有读出电路的 ME 芯片进行了表征。ME 传感器实验验证了在 f = 7.76 kHz 的共振频率下,高达 378 V/T 的高灵敏度的非常线性的响应。测量结果表明,在共振时,传感器的检测极限低至 175 pT/√Hz,这在 MMG 信号范围内。这种小型传感器具有监测慢性运动障碍和提高人机界面的最终用户接受度的潜力。

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