Koep L J, Starzl T E, Weil R
Transplant Proc. 1979 Mar;11(1):257-61.
In this series of 150 orthotopic hepatic transplants, clinically significant gastrointestinal hemorrhage occurred in 34 patients (23%). Five patients (15%) survived this complication. Enteric perforations occurred in 20 patients following 198 biliary-enteric procedures. Only one patient survived. Enteric perforations unrelated to biliary procedures fared only slightly better with one survivor among eight perforations. These results clearly do not warrant complacency. Modifications advocated are an aggressive diagnostic approach and early reoperation with establishment of extensive peritoneal drainage where necessary.
在这一系列150例原位肝移植中,34例患者(23%)发生了具有临床意义的胃肠道出血。5例患者(15%)在该并发症后存活。在198例胆肠吻合术后,20例患者发生了肠穿孔。仅1例患者存活。与胆道手术无关的肠穿孔情况稍好一些,8例穿孔中有1例存活。这些结果显然不容自满。提倡的改进措施是采取积极的诊断方法,并在必要时尽早再次手术,建立广泛的腹腔引流。