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一名感染新型冠状病毒肺炎的儿童发生内脏利什曼病的黏膜复发

Mucosal Relapse of Visceral Leishmaniasis in a Child with SARS-CoV-2 Infection.

作者信息

Colomba Claudia, Boncori Giovanni, Albano Chiara, Garbo Valeria, Bagarello Sara, Condemi Anna, Giordano Salvatore, Cascio Antonio

机构信息

Department of Health Promotion, Maternal and Infant Care, Internal Medicine and Medical Specialties, University of Palermo, 90100 Palermo, Italy.

Division of Pediatric Infectious Diseases, "G. Di Cristina" Hospital, ARNAS Civico Di Cristina Benfratelli, 90100 Palermo, Italy.

出版信息

Pathogens. 2023 Sep 3;12(9):1127. doi: 10.3390/pathogens12091127.

Abstract

Leishmaniasis is a vector-borne disease caused by protozoan parasites of the genus Leishmania and is transmitted through the bite of infected female sandflies. In the Mediterranean region, visceral leishmaniasis is caused by and it is usually responsible for symptoms such as fever, pancytopenia and enlargement of the liver and spleen. Relapse is rare in immunocompetent patients as much as the mucous involvement. We present a rare case of mucosal relapse of visceral leishmaniasis in a child with SARS-CoV-2 infection and perform an extensive review of the literature about leishmaniasis relapses in children. Atypical mucosal involvement during Leishmaniasis relapse is an eventuality in pediatric patients. Clinical follow-up and periodic PCR tests must be considered essential for the early recognition and treatment of an eventual relapse.

摘要

利什曼病是一种由利什曼原虫属的原生动物寄生虫引起的媒介传播疾病,通过受感染的雌性白蛉叮咬传播。在地中海地区,内脏利什曼病由[此处原文缺失病原体信息]引起,通常会导致发热、全血细胞减少以及肝脏和脾脏肿大等症状。免疫功能正常的患者很少复发,黏膜受累情况也不多见。我们报告了1例感染新型冠状病毒肺炎的儿童内脏利什曼病黏膜复发的罕见病例,并对有关儿童利什曼病复发的文献进行了广泛回顾。利什曼病复发时非典型的黏膜受累在儿科患者中是一种可能出现的情况。必须将临床随访和定期PCR检测视为早期识别和治疗可能复发的关键措施。

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