Adam Siti Hajar, Abu Izuddin Fahmy, Kamal Datu Agasi Mohd, Febriza Ami, Kashim Mohd Izhar Ariff Mohd, Mokhtar Mohd Helmy
Preclinical Department, Faculty of Medicine & Defence Health, Universiti Pertahanan Nasional Malaysia, Kuala Lumpur 57000, Malaysia.
Institute of Medical Science Technology, Universiti Kuala Lumpur, Jalan Sultan Ismail, Kuala Lumpur 50250, Malaysia.
Plants (Basel). 2023 Sep 8;12(18):3210. doi: 10.3390/plants12183210.
Obesity has become a worldwide epidemic and its prevalence continues to increase at an alarming rate. It is considered a major risk factor for the development of several comorbidities, including type 2 diabetes, stroke, other cardiovascular diseases and even cancer. Conventional treatments for obesity, such as dietary interventions, exercise and pharmacotherapy, have proven to have limited effectiveness and are often associated with undesirable side effects. Therefore, there is a growing interest in exploring alternative therapeutic approaches. (NS), a medicinal plant with multiple pharmacological properties, has gained attention due to its potential role in the treatment of obesity and its associated complications. The aim of this review is therefore to assess the effects of NS on obesity and its complications and to provide insights into the underlying mechanisms. From this review, NS appears to play a complementary or supportive role in the treatment of obesity and its complications. However, future studies are needed to verify the efficacy of NS in the treatment of obesity and its complications and to prove its safety so that it can be introduced in patients with obesity.
肥胖已成为一种全球性的流行病，其患病率正以惊人的速度持续上升。它被认为是多种合并症发展的主要危险因素，包括2型糖尿病、中风、其他心血管疾病甚至癌症。事实证明，肥胖的传统治疗方法，如饮食干预、运动和药物治疗，效果有限，且常常伴有不良副作用。因此，人们越来越有兴趣探索替代治疗方法。NS是一种具有多种药理特性的药用植物，因其在肥胖及其相关并发症治疗中的潜在作用而受到关注。因此，本综述的目的是评估NS对肥胖及其并发症的影响，并深入探讨其潜在机制。从本综述来看，NS似乎在肥胖及其并发症的治疗中发挥着补充或支持作用。然而，未来还需要开展研究来验证NS治疗肥胖及其并发症的疗效，并证明其安全性，以便能够将其应用于肥胖患者。
