Raksiri Chana, Potejanasak Potejana, Dokyor Thitipoom
Department of Industrial Engineering, Faculty of Engineering, Kasetsart University, Bangkok 10900, Thailand.
Department of Industrial Engineering, School of Engineering, University of Phayao, Phayao 56000, Thailand.
Polymers (Basel). 2023 Sep 18;15(18):3804. doi: 10.3390/polym15183804.
The fabrication of nanostructures is of great importance in producing biomedical devices. Significantly, the nanostructure of the polymeric film has a significant impact on the physical and biophysical behavior of the biomolecules. This study presents an efficient nanofabrication method of nanogroove structures on an acrylic film by the micro-embossing process. In this method, a master mold was made from a thermos oxide silicon substrate using photolithography and etching techniques. An isotropic optical polymethyl methacrylate (PMMA) film is used in the experiment. The acrylic film is known for its excellent optical properties in products such as optical lenses, medical devices, and various general purpose engineering plastics. Then, the micro-embossing process was realized to fabricate nanogroove patterns on an acrylic film by using a micro-embossing machine. However, the morphology of the nanopatterns on an acrylic film was characterized by using an atomic force microscope to measure the dimensions of the nanogroove patterns. The impact of embossing temperature on the morphology of nanogroove patterns on acrylic film is experimentally investigated. The results show that when the embossing temperature is too small, the pattern is not fully formed, and slipping occurs in nanopatterns on the acrylic film. On the other hand, the effect of increasing the embossing temperature on the morphology of nanogrooves agrees with the master mold, and the crests between the nanogrooves form straight edges. It should be noted that the micro-embossing temperature also strongly influences the transferability of nanopatterns on an acrylic film. The technique has great potential for rapidly fabricating nanostructure patterns on acrylic film.
纳米结构的制造在生物医学设备生产中具有重要意义。值得注意的是，聚合物薄膜的纳米结构对生物分子的物理和生物物理行为有重大影响。本研究提出了一种通过微压印工艺在丙烯酸薄膜上制备纳米凹槽结构的高效纳米制造方法。在该方法中，使用光刻和蚀刻技术由热氧化硅衬底制作母模。实验中使用各向同性光学聚甲基丙烯酸甲酯（PMMA）薄膜。丙烯酸薄膜在光学镜片、医疗设备和各种通用工程塑料等产品中以其优异的光学性能而闻名。然后，通过使用微压印机在丙烯酸薄膜上实现微压印工艺以制造纳米凹槽图案。然而，通过使用原子力显微镜测量纳米凹槽图案的尺寸来表征丙烯酸薄膜上纳米图案的形态。实验研究了压印温度对丙烯酸薄膜上纳米凹槽图案形态的影响。结果表明，当压印温度过小时，图案未完全形成，丙烯酸薄膜上的纳米图案会出现滑移。另一方面，提高压印温度对纳米凹槽形态的影响与母模一致，纳米凹槽之间的波峰形成直边。应当指出，微压印温度也强烈影响纳米图案在丙烯酸薄膜上的可转移性。该技术在快速制造丙烯酸薄膜上的纳米结构图案方面具有巨大潜力。
