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巴基斯坦按性别划分的精神障碍负担:1990 - 2019年全球疾病负担研究数据分析

Burden of mental disorders by gender in Pakistan: analysis of Global Burden of Disease Study data for 1990-2019.

作者信息

Alvi Mohsin Hassan, Ashraf Tehmina, Naz Farah, Sardar Asif, Ullah Akbar, Patel Anita, Kiran Tayyeba, Gumber Anil, Husain Nusrat

机构信息

Pakistan Institute of Living and Learning, Rawalpindi, Pakistan.

University of Manchester, Manchester, UK.

出版信息

BJPsych Bull. 2023 Sep 29;48(6):1-8. doi: 10.1192/bjb.2023.76.

Abstract

AIMS AND METHOD

We aimed to examine the burden of mental disorders in Pakistan over the past three decades. We used the crude data of disability-adjusted life-years (DALYs) obtained from the Global Burden of Disease Study database (1990-2019) to represent burden. Data were retrieved on 26 January 2021. Data for adults of reproductive age (aged 15-49 years) were analysed to discuss and interpret the disease burden. An analysis was conducted on total DALYs separately for the genders for ten mental disorders reported in Pakistan.

RESULTS

DALYs increased drastically with the onset of reproductive age. Depressive disorder was the most reported mental disorder, contributing 3.13% (95% CI 2.25-4.24) of total DALYs, and varied significantly between genders: females 3.89% (95% CI 2.73-5.29) versus males 2.37% (95% CI 1.62-3.25).

CLINICAL IMPLICATIONS

A nationwide high-quality epidemiological surveillance system should be implemented to monitor mental disorders and offer culturally appropriate preventive services.

摘要

目的与方法

我们旨在研究巴基斯坦过去三十年精神障碍的负担情况。我们使用从全球疾病负担研究数据库(1990 - 2019年)获取的残疾调整生命年(DALYs)的原始数据来代表负担情况。数据于2021年1月26日检索。对育龄成年人(15 - 49岁)的数据进行分析,以讨论和解释疾病负担。分别对巴基斯坦报告的十种精神障碍按性别对总DALYs进行了分析。

结果

DALYs随着育龄期的开始而急剧增加。抑郁症是报告最多的精神障碍,占总DALYs的3.13%(95%置信区间2.25 - 4.24),并且在性别之间存在显著差异:女性为3.89%(95%置信区间2.73 - 5.29),而男性为2.37%(95%置信区间1.62 - 3.25)。

临床意义

应实施全国性的高质量流行病学监测系统,以监测精神障碍并提供符合文化背景的预防服务。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b41/11669452/bcfef35448c0/S2056469423000761_fig1.jpg

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