Guendulain Corina, Tamiozzo Pablo, González Griselda, Caffaratti Marina
Universidad Nacional de Río Cuarto.
Rev Fac Cien Med Univ Nac Cordoba. 2023 Sep 29;80(3):175-187. doi: 10.31053/1853.0605.v80.n3.36769.
Helicobacter is a genus of Gram-negative bacteria that colonizes the stomach of humans and dogs, among other mammals. The most frequent species found in the gastric mucosa of man is H. pylori, however, there are other species of Helicobacter in the stomach of humans, such as H. suis, H. bizzozeronii, H. felis, H. salomonis and H. heilmannii sensu stricto, named non H. pylori Helicobacter (NHPH) some of which also colonize the dog's stomach. The detection of NHPH in the stomach mucosa of humans with gastric disease, and in a high percentage of dogs, suggests the possibility that these animals play an important role in the pathogenesis and transmission of infection to man, postulating the path of transmission oral-oral or fecal-oral. The aim of this study was to determine whether people with signs of chronic gastritis who have Helicobacter spp. and who own dogs as pets, share the same species with them. The presence of Helicobacter spp. in gastric samples of 30 people with clinical signs of chronic gastritis and histopathological diagnosis of gastric infection with Helicobacter spp. was analyzed by PCR. The presence of Helicobacter spp. was also studied in the dogs of these people. Then, the species of Helicobacter presented was determined in both. In human gastric samples, H. pylori was the only species found, while in dogs, samples were H. bizzozeronii, H. felis, H. salomonis and H. heilmannii. In this work the same species were not found in dogs and their owners.
幽门螺杆菌是一种革兰氏阴性菌属，可在人类、犬类以及其他哺乳动物的胃中定殖。在人类胃黏膜中发现最常见的菌种是幽门螺杆菌（H. pylori），然而，人类胃中还存在其他幽门螺杆菌菌种，如猪幽门螺杆菌（H. suis）、比氏幽门螺杆菌（H. bizzozeronii）、猫幽门螺杆菌（H. felis）、所罗门幽门螺杆菌（H. salomonis）和狭义的海尔曼幽门螺杆菌（H. heilmannii sensu stricto），这些被称为非幽门螺杆菌幽门螺杆菌（NHPH），其中一些也定殖于犬类的胃中。在患有胃部疾病的人类胃黏膜中以及在高比例的犬类中检测到NHPH，这表明这些动物可能在感染人类的发病机制和传播中发挥重要作用，并推测其传播途径为口口传播或粪口传播。本研究的目的是确定患有慢性胃炎体征且感染幽门螺杆菌属并将犬类作为宠物饲养的人是否与犬类携带相同的菌种。通过聚合酶链反应（PCR）分析了30名有慢性胃炎临床体征且经组织病理学诊断为幽门螺杆菌属胃部感染的人的胃样本中幽门螺杆菌属的存在情况。还研究了这些人的犬类中幽门螺杆菌属的存在情况。然后，确定了两者中所呈现的幽门螺杆菌菌种。在人类胃样本中，仅发现了幽门螺杆菌，而在犬类样本中，发现的菌种为比氏幽门螺杆菌、猫幽门螺杆菌、所罗门幽门螺杆菌和海尔曼幽门螺杆菌。在本研究中，未在犬类及其主人中发现相同的菌种。
