Lepape A, Sarron C, Grozel J M, Perdrix J P, Banssillon V
Ann Fr Anesth Reanim. 1986;5(4):441-4. doi: 10.1016/s0750-7658(86)80015-6.
A case of a severe heat stroke is reported in a 30 yr old white man while running a long-distance race. At the time of admission, moderate hyperthermia (40 degrees C) and coma were two major symptoms found at physical examination. Within 24 h, the clinical picture evolved to multiple organ failure with marked rhabdomyolysis, acute renal failure with hyperkalaemia and lactic acidosis. At this time, were also found a consumptive coagulopathy and acute hepatic failure. After numerous complications, most of them infectious, the patient was discharged after four months in ICU and admitted in a physical rehabilitation department. Muscle biopsy performed three years after the heat stroke showed an abnormal reactivity to caffeine, but a normal reaction to halothane. The relationship between malignant hyperthermia and heat stroke remains uncertain.
一名30岁白人男性在参加长跑比赛时发生严重中暑的病例被报道。入院时，体格检查发现中度体温过高（40摄氏度）和昏迷是两大主要症状。在24小时内，临床症状发展为多器官功能衰竭，伴有明显的横纹肌溶解、伴有高钾血症和乳酸性酸中毒的急性肾衰竭。此时，还发现了消耗性凝血病和急性肝衰竭。在出现众多并发症（其中大多数为感染性并发症）后，患者在重症监护病房住了四个月后出院，并入住物理康复科。中暑三年后进行的肌肉活检显示对咖啡因反应异常，但对氟烷反应正常。恶性高热与中暑之间的关系仍不确定。
