Kenneally Laura Fuertes, Lorenzo Miguel, Romero-González Gregorio, Cobo Marta, Núñez Gonzalo, Górriz Jose Luis, Barrios Ana Garcia, Fudim Marat, de la Espriella Rafael, Núñez Julio
Cardiology Department, General Hospital of Alicante, Dr Balmis. Alicante, Spain.
Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL). Alicante, Spain.
Clin Kidney J. 2023 Feb 20;16(10):1587-1599. doi: 10.1093/ckj/sfad031. eCollection 2023 Oct.
Worsening kidney function (WKF) is common in patients with acute heart failure (AHF) syndromes. Although WKF has traditionally been associated with worse outcomes on a population level, serum creatinine concentrations vary greatly during episodes of worsening heart failure, with substantial individual heterogeneity in terms of their clinical meaning. Consequently, interpreting such changes within the appropriate clinical context is essential to unravel the pathophysiology of kidney function changes and appropriately interpret their clinical meaning. This article aims to provide a critical overview of WKF in AHF, aiming to provide physicians with some tips and tricks to appropriately interpret kidney function changes in the context of AHF.
肾功能恶化（WKF）在急性心力衰竭（AHF）综合征患者中很常见。尽管传统上认为WKF在总体人群中与更差的预后相关，但在心力衰竭恶化发作期间血清肌酐浓度变化很大，其临床意义存在显著的个体异质性。因此，在适当的临床背景下解读此类变化对于阐明肾功能变化的病理生理学并正确解读其临床意义至关重要。本文旨在对AHF中的WKF进行批判性综述，旨在为医生提供一些提示和技巧，以便在AHF背景下正确解读肾功能变化。
