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健康饮食指数-2015得分及体育活动对新冠病毒病结局的有益作用。

Beneficial role of healthy eating Index-2015 score & physical activity on COVID-19 outcomes.

作者信息

Hegazy Mona A, Fouad Marwa M, Abd Elshafy Samah Ahmed, Abdelfatah Dalia, Lithy Rania M, Abdelghani Ahmed, Ashoush Omar Ahmed

机构信息

Internal medicine department, faculty of medicine, Cairo University, Cairo, 11562, Egypt.

Occupational and Environmental medicine department, Cairo University, Cairo, Egypt.

出版信息

BMC Nutr. 2023 Oct 2;9(1):113. doi: 10.1186/s40795-023-00727-8.

Abstract

BACKGROUND

Nutritional status and physical activity are essential to maintain a strong immune system. No definite pharmacological strategies for Coronavirus disease 2019 treatment are presently available, so natural enhancement of the immune system is in need. Our goal was to assess the correlation of healthy diet and physical activity on COVID-19 disease outcome.

METHODS

This cohort study was conducted on 68 adult patients who contracted mild (38) or moderate [30] cases of COVID-19, recruited via a convenience sampling technique from the outpatient clinic, Kasr Al-Aini Faculty of Medicine, Cairo University Hospital. Patients' Healthy Eating Index (HEI) and degree of physical activity as measured by the Global Physical Activity Questionnaire were evaluated and linked with several inflammatory markers.

RESULTS

Most of patients with mild COVID-19 patients (92.1%) were physically active, compared to only 50% of moderate COVID-19. The total Metabolic Equivalent Task-min/week was positively correlated with the lymphocyte percentage. The median total HEI score was significantly higher in the patients with mild COVID-19 than with moderate COVID. Significant positive correlations observed among the lymphocyte count and total HEI-2015. There was approximately a 64% reduction in the probability of acquiring moderate COVID-19 illness for each unit rise in The HEI.

CONCLUSION

Healthier nutrition and Physical activity correlated with reduced COVID-19 disease severity.

TRIAL REGISTRATION

The study was registered on clinical trial.gov maintained by the US National Library of Medicine (CinicalTrials.gov identifier = NCT04447144; https://clinicaltrials.gov/ ) (25/06/2020).

摘要

背景

营养状况和身体活动对于维持强大的免疫系统至关重要。目前尚无明确的2019冠状病毒病治疗药理学策略,因此需要自然增强免疫系统。我们的目标是评估健康饮食和身体活动与COVID-19疾病结局的相关性。

方法

本队列研究对68例感染轻度(38例)或中度(30例)COVID-19的成年患者进行,通过便利抽样技术从开罗大学医院卡斯尔·艾尼医学院门诊招募。评估患者的健康饮食指数(HEI)和通过全球身体活动问卷测量的身体活动程度,并将其与多种炎症标志物相关联。

结果

大多数轻度COVID-19患者(92.1%)身体活跃,而中度COVID-19患者中这一比例仅为50%。每周总代谢当量任务分钟数与淋巴细胞百分比呈正相关。轻度COVID-19患者的HEI总分中位数显著高于中度COVID-19患者。淋巴细胞计数与总HEI-2015之间存在显著正相关。HEI每增加一个单位,患中度COVID-19疾病的概率大约降低64%。

结论

更健康的营养和身体活动与降低COVID-19疾病严重程度相关。

试验注册

该研究已在美国国立医学图书馆维护的clinicaltrial.gov上注册(ClinicalTrials.gov标识符=NCT04447144;https://clinicaltrials.gov/ )(2020年6月25日)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/944b/10546692/12ced61073e6/40795_2023_727_Figa_HTML.jpg

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