Khatri Shivam, Xerras Michael, Chamay Salomon, Sharma Shorabh
CUNY School of Medicine, New York, NY 10031, USA.
Division of Internal Medicine, Department of Medicine, St. Barnabas Hospital, Bronx, NY 10457, USA.
Radiol Case Rep. 2023 Sep 26;18(12):4318-4322. doi: 10.1016/j.radcr.2023.09.020. eCollection 2023 Dec.
Acute disseminated encephalomyelitis (ADEM) is a rare immune-mediated demyelinating disorder primarily observed in children, typically triggered by recent vaccination or viral infection. Although uncommon, there have been reports of ADEM occurring in adults, with varying radiological findings compared to pediatric cases. Distinguishing ADEM from other demyelinating disorders, such as multiple sclerosis (MS) and neuromyelitis optica (NMO), can pose a diagnostic challenge. We present a case report of an 18-year-old male with a history of polysubstance use who was successfully treated with corticosteroids and highlight the neuroradiological presentation of ADEM, emphasizing the importance of accurate diagnosis and management in both pediatric and adult populations.
急性播散性脑脊髓炎（ADEM）是一种罕见的免疫介导性脱髓鞘疾病，主要见于儿童，通常由近期接种疫苗或病毒感染引发。虽然不常见，但也有成人发生ADEM的报道，与儿童病例相比，其影像学表现各异。将ADEM与其他脱髓鞘疾病，如多发性硬化（MS）和视神经脊髓炎（NMO）相鉴别，可能会带来诊断挑战。我们报告一例有多种物质使用史的18岁男性病例，该患者接受皮质类固醇治疗成功，并强调了ADEM的神经影像学表现，突出了在儿童和成人人群中准确诊断和管理的重要性。
