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经颅磁刺激治疗脑卒中后上肢运动功能障碍的临床研究进展

Clinical Research Progress of the Post-Stroke Upper Limb Motor Function Improvement via Transcutaneous Auricular Vagus Nerve Stimulation.

机构信息

Department of Rehabilitation Medicine, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, 200336, Shanghai, China.

Institute of Rehabilitation, Shanghai Jiao Tong University School of Medicine, 200025, Shanghai, China.

出版信息

Neural Plast. 2023 Sep 25;2023:9532713. doi: 10.1155/2023/9532713. eCollection 2023.

DOI:10.1155/2023/9532713
PMID:37789954
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10545466/
Abstract

Stroke is a disease with high morbidity and disability, and motor impairment is a common sequela of stroke. Transcutaneous auricular vagus nerve stimulation (taVNS) is a type of non-invasive stimulation, which can effectively improve post-stroke motor dysfunction. This review discusses stimulation parameters, intervention timing, and the development of innovative devices for taVNS. We further summarize the application of taVNS in improving post-stroke upper limb motor function to further promote the clinical research and application of taVNS in the rehabilitation of post-stroke upper limb motor dysfunction.

摘要

脑卒中是一种高发病率和高致残率的疾病,运动功能障碍是脑卒中的常见后遗症。经皮耳迷走神经刺激(taVNS)是一种非侵入性刺激方法,可有效改善脑卒中后的运动功能障碍。本综述讨论了 taVNS 的刺激参数、干预时机和创新设备的发展。我们进一步总结了 taVNS 在改善脑卒中后上肢运动功能中的应用,以进一步促进 taVNS 在脑卒中后上肢运动功能障碍康复中的临床研究和应用。

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本文引用的文献

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Vagus nerve stimulation paired with rehabilitation for motor function, mental health and activities of daily living after stroke: a systematic review and meta-analysis.迷走神经刺激联合康复治疗对卒中后运动功能、心理健康及日常生活活动能力的影响:一项系统评价与Meta分析
J Neurol Neurosurg Psychiatry. 2023 Apr;94(4):257-266. doi: 10.1136/jnnp-2022-329275. Epub 2022 Dec 5.
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Auricular vagus nerve stimulator for closed-loop biofeedback-based operation.用于基于闭环生物反馈操作的耳迷走神经刺激器。
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Closed-Loop Transcutaneous Auricular Vagal Nerve Stimulation: Current Situation and Future Possibilities.闭环经皮耳迷走神经刺激:现状与未来可能性
Front Hum Neurosci. 2022 Jan 4;15:785620. doi: 10.3389/fnhum.2021.785620. eCollection 2021.
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Efficacy and safety of transcutaneous auricular vagus nerve stimulation combined with conventional rehabilitation training in acute stroke patients: a randomized controlled trial conducted for 1 year involving 60 patients.经皮耳迷走神经刺激联合传统康复训练对急性脑卒中患者的疗效及安全性:一项为期1年的随机对照试验,纳入60例患者。
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World Stroke Organization (WSO): Global Stroke Fact Sheet 2022.世界卒中组织(WSO):全球卒中状况 2022 概要。
Int J Stroke. 2022 Jan;17(1):18-29. doi: 10.1177/17474930211065917.
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Transcutaneous auricular vagus nerve stimulators: a review of past, present, and future devices.经皮耳迷走神经刺激器:过去、现在和未来设备的综述。
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7
Transcutaneous Auricular Vagus Nerve Stimulation (tAVNS) Delivered During Upper Limb Interactive Robotic Training Demonstrates Novel Antagonist Control for Reaching Movements Following Stroke.在上肢交互式机器人训练期间进行的经皮耳迷走神经刺激(tAVNS)显示出对中风后伸手动作的新型拮抗控制。
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