Cheng Chak Kwong, Huang Yu
Department of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, China.
Med Rev (2021). 2023 Jun 22;3(3):209-213. doi: 10.1515/mr-2023-0015. eCollection 2023 Jun.
Our oral cavity houses various types of microbes including bacteria, protozoa, fungi and viruses, harboring over 700 bacterial species. Oral dysbiosis refers to the imbalance between symbionts and pathobionts in the oral cavity, posing potential threats to host cardiovascular health. Importantly, oral dysbiosis promotes cardiovascular pathophysiology through different mechanisms. Although overgrowth of certain pathogenic bacteria have been indicated in some cardiometabolic diseases, it is still premature to consider oral microbiome as a suitable predictor for non-invasive diagnostic purpose. However, targeting oral microbiome might still provide preventive and therapeutic insights on cardiovascular diseases. Further extensive efforts are needed to deepen our understanding on oral-cardiovascular connection in the context of diagnostic and therapeutic perspectives.
我们的口腔中存在各种类型的微生物，包括细菌、原生动物、真菌和病毒，有超过700种细菌。口腔生态失调是指口腔中共生菌和致病共生菌之间的失衡，对宿主心血管健康构成潜在威胁。重要的是，口腔生态失调通过不同机制促进心血管病理生理过程。尽管在一些心脏代谢疾病中已表明某些病原菌过度生长，但将口腔微生物群视为非侵入性诊断的合适预测指标仍为时过早。然而，针对口腔微生物群仍可能为心血管疾病提供预防和治疗思路。需要进一步广泛努力，从诊断和治疗角度加深我们对口腔与心血管联系的理解。
