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Rationale for the Use of Homologous Recombination Proficient Molecular Profile as a Biomarker for Therapeutic Targeting in Ovarian Cancer.

作者信息

Nemunaitis John, Stanbery Laura, Walter Adam, Rocconi Rodney, Stephens Philip

机构信息

Gradalis, Inc, Dallas, TX, United States.

ProMedica, Toledo, OH, United States.

出版信息

Oncol Rev. 2023 Sep 20;17:11471. doi: 10.3389/or.2023.11471. eCollection 2023.

DOI:10.3389/or.2023.11471
PMID:37799595
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10547877/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6c8/10547877/8a824122e34d/or-17-11471-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6c8/10547877/8a824122e34d/or-17-11471-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6c8/10547877/8a824122e34d/or-17-11471-g001.jpg

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Am J Clin Oncol. 2023 Sep 1;46(9):414-419. doi: 10.1097/COC.0000000000001024. Epub 2023 Jun 12.
2
Ovarian Cancer Therapy: Homologous Recombination Deficiency as a Predictive Biomarker of Response to PARP Inhibitors.卵巢癌治疗:同源重组缺陷作为预测对PARP抑制剂反应的生物标志物
Onco Targets Ther. 2022 Oct 4;15:1105-1117. doi: 10.2147/OTT.S272199. eCollection 2022.
3
A phenotypic signature that identifies neoantigen-reactive T cells in fresh human lung cancers.
Cancers (Basel). 2023 Nov 28;15(23):5616. doi: 10.3390/cancers15235616.
一种表型特征可鉴定新鲜人肺癌中的新抗原反应性 T 细胞。
Cancer Cell. 2022 May 9;40(5):479-493.e6. doi: 10.1016/j.ccell.2022.03.012. Epub 2022 Apr 21.
4
Homologous Recombination Deficiency Associated With Response to Poly (ADP-ribose) Polymerase Inhibitors in Ovarian Cancer Patients: The First Real-World Evidence From China.同源重组缺陷与卵巢癌患者对聚(ADP - 核糖)聚合酶抑制剂的反应相关:来自中国的首个真实世界证据
Front Oncol. 2022 Jan 6;11:746571. doi: 10.3389/fonc.2021.746571. eCollection 2021.
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BMC Cancer. 2021 Oct 28;21(1):1154. doi: 10.1186/s12885-021-08863-9.
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