Peptenatu D, Nedelcu I D, Pop C S, Simion A G, Furtunescu F, Burcea M, Andronache I, Radulovic M, Jelinek H F, Ahammer H, Gruia A K, Grecu A, Popa M C, Militaru V, Drăghici C C, Pintilii R D
Research Center for Integrated Analysis and Territorial Management-CAIMT Faculty of Geography University of Bucharest Bucharest Romania.
Carol Davila University of Medicine and Pharmacy Bucharest Romania.
Geohealth. 2023 Oct 4;7(10):e2023GH000901. doi: 10.1029/2023GH000901. eCollection 2023 Oct.
The objective of this study was to identify spatial disparities in the distribution of cancer hotspots within Romania. Additionally, the research aimed to track prevailing trends in cancer prevalence and mortality according to a cancer type. The study covered the timeframe between 2008 and 2017, examining all 3,181 territorial administrative units. The analysis of spatial distribution relied on two key parameters. The first parameter, persistence, measured the duration for which cancer prevalence exceeded the 75th percentile threshold. Cancer prevalence refers to the total number of individuals in a population who have been diagnosed with cancer at a specific time point, including both newly diagnosed cases (occurrence) and existing cases. The second parameter, the time continuity of persistence, calculated the consecutive months during which cancer prevalence consistently surpassed the 75th percentile threshold. Notably, persistence of elevated values was also evident in lowland regions, devoid of any discernible direct connection to environmental conditions. In conclusion, this work bears substantial relevance to regional health policies, by aiding in the formulation of prevention strategies, while also fostering a deeper comprehension of the socioeconomic and environmental factors contributing to cancer.
本研究的目的是确定罗马尼亚境内癌症热点分布的空间差异。此外，该研究旨在追踪不同癌症类型的癌症患病率和死亡率的流行趋势。该研究涵盖了2008年至2017年的时间段，对所有3181个领土行政单位进行了考察。空间分布分析依赖于两个关键参数。第一个参数是持续性，它衡量癌症患病率超过第75百分位数阈值的持续时间。癌症患病率是指在特定时间点被诊断患有癌症的人群总数，包括新诊断病例（发病率）和现有病例。第二个参数是持续性的时间连续性，它计算癌症患病率持续超过第75百分位数阈值的连续月数。值得注意的是，在低地地区也明显存在数值升高的持续性，且与环境条件没有任何明显的直接联系。总之，这项工作对区域卫生政策具有重大意义，有助于制定预防策略，同时也能促进对导致癌症的社会经济和环境因素的更深入理解。
