基于干细胞的组织工程修复材料促进体表慢性难愈创面愈合的研究进展
[Research advances of stem cell-based tissue engineering repair materials in promoting the healing of chronic refractory wounds on the body surface].
作者信息
Peng Y, Meng H, Li P X, Jiang Y F, Fu X B
机构信息
Research Center for Wound Repair and Tissue Regeneration, Medical Innovation Research Department, the PLA General Hospital, Beijing 100048, China.
School of Medicine, Nankai University, Tianjin 300071, China.
出版信息
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2023 Mar 20;39(3):290-295. doi: 10.3760/cma.j.cn501225-20220407-00126.
Repairing chronic refractory wounds on the body surface is a complex medical problem involving all stages of wound healing. In recent years, stem cells (SCs) and tissue engineering (TE) have brought hope for repairing chronic refractory wounds. SCs have excellent regenerative and paracrine effects; various TE strategies have the potential to repair chronic refractory wounds on the body surface and also improve the delivery efficiency of SCs. This article reviews the pathological characteristics of chronic refractory wounds, SCs used to repair chronic refractory wounds, and SC-based TE wound repair strategies.
修复体表慢性难愈性伤口是一个涉及伤口愈合各个阶段的复杂医学问题。近年来，干细胞和组织工程为修复慢性难愈性伤口带来了希望。干细胞具有出色的再生和旁分泌作用；各种组织工程策略有修复体表慢性难愈性伤口的潜力，还能提高干细胞的递送效率。本文综述了慢性难愈性伤口的病理特征、用于修复慢性难愈性伤口的干细胞以及基于干细胞的组织工程伤口修复策略。
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