细胞黏菌紫多头绒泡菌聚集素的初步特性分析。
Preliminary characterization of the acrasin of the cellular slime mold Polysphondylium violaceum.
作者信息
Wurster B, Pan P, Tyan G G, Bonner J T
出版信息
Proc Natl Acad Sci U S A. 1976 Mar;73(3):795-9. doi: 10.1073/pnas.73.3.795.
Some species of cellular slime mold do not respond to cyclic AMP as an acrasin, or chemoattractant. In one such species, Polysphondylium violaceum, we have isolated and purified its acrasin and determined some of its chemical properties, which lead us to believe it is a small molecule of less than 1500 daltons. One possibility is that it might be a peptide. The acrasin specifically attracts the amoebae of P. violaceum and P. pallidum and fails to do so for six species of Dictyostelium tested. We also have evidence for a specific acrasinase that inactivates the Polysphondylium acrasin.
某些细胞黏菌物种对作为聚集素或化学引诱剂的环磷酸腺苷（cAMP）没有反应。在其中一个这样的物种——紫多头绒泡菌（Polysphondylium violaceum）中，我们已经分离并纯化了它的聚集素，并确定了它的一些化学性质，这使我们相信它是一个分子量小于1500道尔顿的小分子。一种可能性是它可能是一种肽。这种聚集素能特异性地吸引紫多头绒泡菌和苍白多头绒泡菌（P. pallidum）的变形虫，而对所测试的六种盘基网柄菌（Dictyostelium）物种则没有这种作用。我们还有证据表明存在一种特异性的聚集素酶，它能使紫多头绒泡菌的聚集素失活。
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