Botto Inês, Moiteiro Cruz Rafael, Noronha Ferreira Carlos, Valente Ana Isabel, Carrilho-Ribeiro Luis, Tato-Marinho Rui, Ferreira Cristina, Correia Luis
Serviço de Gastrenterologia e Hepatologia, Hospital Santa Maria, Centro Hospitalar Universitário Lisboa Norte, EPE, Lisbon, Portugal.
Serviço de Anatomia Patológica, Hospital Santa Maria, Centro Hospitalar Universitário Lisboa Norte, EPE, Lisbon, Portugal.
ACG Case Rep J. 2023 Oct 5;10(10):e01168. doi: 10.14309/crj.0000000000001168. eCollection 2023 Oct.
Although breast cancer (BC) is the most common malignancy in women, metastasization to the gastrointestinal tract is rare. We present a 59-year-old woman with simultaneous gastric and colonic metastasis of invasive lobular breast carcinoma. She had been diagnosed with BC and underwent surgery and systemic therapy. Two years later, an increase in tumor markers motivated investigation, including upper and lower gastrointestinal endoscopy, which identified gastric ulcers and mucosal irregularity in the cecum. Histopathological analysis was compatible with gastric and colonic metastases from BC. We highlight the importance of biopsying every endoscopically visible lesion in patients with BC history.
尽管乳腺癌(BC)是女性中最常见的恶性肿瘤,但胃肠道转移却很少见。我们报告一名59岁女性,患有浸润性小叶乳腺癌同时发生胃和结肠转移。她曾被诊断为乳腺癌并接受了手术和全身治疗。两年后,肿瘤标志物升高促使进行检查,包括上消化道和下消化道内镜检查,发现胃溃疡和盲肠黏膜不规则。组织病理学分析与乳腺癌的胃和结肠转移相符。我们强调,对于有乳腺癌病史的患者,对每个内镜可见病变进行活检的重要性。