Stern R M, Koch K L, Stewart W R, Lindblad I M
Gastroenterology. 1987 Jan;92(1):92-7. doi: 10.1016/0016-5085(87)90843-2.
The purpose of the present experiment was to study frequency changes in gastric myoelectric activity of healthy human subjects and the development of symptoms of motion sickness as brought about by vection or illusory self-motion. Fifteen fasted healthy human subjects were seated inside a circular vection drum, the rotation of which produces visual signals of self-motion that are in conflict with vestibular signals (i.e., mismatched sensory input). An electrogastrogram was obtained for three 15-min. periods: baseline, rotation, and after drum rotation stopped. Respiration, symptoms volunteered by subjects, and a continuous measure of intensity of symptoms were recorded. Five subjects showed a continuation of normal 3-cycles/min. activity during drum rotation and reported no symptoms of motion sickness. Ten subjects showed a shift of their dominant gastric frequency from 3 cycles/min. to 4-9 cycles/min. during drum rotation and reported symptoms of motion sickness. Running spectral analysis revealed a close correspondence over time between tachygastria and reports of symptoms of motion sickness.
本实验的目的是研究健康人体受试者胃肌电活动的频率变化，以及由相对运动或虚幻自我运动引起的晕动病症状的发展。15名空腹的健康人体受试者坐在一个圆形的相对运动鼓内，鼓的旋转会产生与前庭信号相冲突的自我运动视觉信号（即不匹配的感觉输入）。在三个15分钟的时间段内获取胃电图：基线期、旋转期和鼓停止旋转后。记录呼吸、受试者自发的症状以及症状强度的连续测量值。5名受试者在鼓旋转期间表现出正常的每分钟3次循环的活动持续存在，并且未报告晕动病症状。10名受试者在鼓旋转期间其主要胃频率从每分钟3次循环转变为每分钟4 - 9次循环，并报告了晕动病症状。运行频谱分析显示，心动过速与晕动病症状报告之间随时间存在密切对应关系。
