Llamas K J, Torlach L G, Ward M, Bain C
Gut. 1986 Oct;27(10):1181-5. doi: 10.1136/gut.27.10.1181.
Seventy two patients (39 women) with colonic adenomas were compared with 72 adenoma free controls (39 women) to investigate the possible association between previous cholecystectomy and the subsequent development of adenomas. Data were gathered retrospectively from medical records. Overall there was no significant association between colonic adenomas and previous cholecystectomy. When women are considered separately, however, eight cases and no controls had undergone cholecystectomy (odds ratio infinity lower 95% confidence limits 1.7, p greater than 0.01). No association between previous cholecystectomy and large bowel adenomas was found in men. Four of nine (44.4%) women with right sided colonic adenomas had undergone previous cholecystectomy compared with only three of 23 (13%) women with left sided adenomas.
72例患有结肠腺瘤的患者(39名女性)与72名无腺瘤的对照者(39名女性)进行比较,以研究既往胆囊切除术与随后腺瘤发生之间的可能关联。数据从医疗记录中回顾性收集。总体而言,结肠腺瘤与既往胆囊切除术之间无显著关联。然而,单独考虑女性时,有8例患者接受过胆囊切除术,而对照者中无人接受过(优势比无穷大,95%置信下限1.7,p>0.01)。在男性中未发现既往胆囊切除术与大肠腺瘤之间存在关联。右侧结肠腺瘤的9名女性中有4名(44.4%)既往接受过胆囊切除术,而左侧腺瘤的23名女性中只有3名(13%)接受过。