实验室检查在震颤分类中的作用。
The role of laboratory investigations in the classification of tremors.
机构信息
Department of Human Neurosciences, Sapienza University of Rome, Viale Dell'Università 30, 00185, Rome, Italy.
Department of Medical, Surgical Sciences and Advanced Technologies "GF Ingrassia," University of Catania, Catania, Italy.
出版信息
Neurol Sci. 2023 Dec;44(12):4183-4192. doi: 10.1007/s10072-023-07108-w. Epub 2023 Oct 10.
INTRODUCTION
Tremor is the most common movement disorder. Although clinical examination plays a significant role in evaluating patients with tremor, laboratory tests are useful to classify tremors according to the recent two-axis approach proposed by the International Parkinson and Movement Disorders Society.
METHODS
In the present review, we will discuss the usefulness and applicability of the various diagnostic methods in classifying and diagnosing tremors. We will evaluate a number of techniques, including laboratory and genetic tests, neurophysiology, and neuroimaging. The role of newly introduced innovative tremor assessment methods will also be discussed.
RESULTS
Neurophysiology plays a crucial role in tremor definition and classification, and it can be useful for the identification of specific tremor syndromes. Laboratory and genetic tests and neuroimaging may be of paramount importance in identifying specific etiologies. Highly promising innovative technologies are being developed for both clinical and research purposes.
CONCLUSIONS
Overall, laboratory investigations may support clinicians in the diagnostic process of tremor. Also, combining data from different techniques can help improve understanding of the pathophysiological bases underlying tremors and guide therapeutic management.
简介
震颤是最常见的运动障碍。虽然临床检查在评估震颤患者方面起着重要作用，但实验室检查有助于根据国际帕金森和运动障碍协会最近提出的双轴方法对震颤进行分类。
方法
在本综述中，我们将讨论各种诊断方法在分类和诊断震颤方面的有用性和适用性。我们将评估包括实验室和遗传测试、神经生理学和神经影像学在内的多种技术。还将讨论新引入的创新震颤评估方法的作用。
结果
神经生理学在震颤的定义和分类中起着至关重要的作用，它可有助于识别特定的震颤综合征。实验室和遗传测试以及神经影像学在确定特定病因方面可能至关重要。正在为临床和研究目的开发极有前途的创新技术。
结论
总体而言，实验室研究可能有助于临床医生进行震颤的诊断过程。此外，结合来自不同技术的数据可以帮助更好地了解震颤的病理生理基础，并指导治疗管理。
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