Elyasi Boshra, Nasarolahzade Masouleh Mohammad, Jahandideh Alireza
Department of Clinical Science, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Vet Res Forum. 2023;14(9):495-499. doi: 10.30466/vrf.2022.552942.3456. Epub 2023 Sep 15.
Ovariohysterectomy (OHE) is one of the most common surgeries in veterinary medicine. Although this surgical method has several advantages, it can alter the function of various organs such as heart. The present study investigated the effect of OHE on cardiac functions using M-mode echocardiography. A total of 10 healthy adult domestic short-haired cats were enrolled in the current study. Fractional shortening (FS) and ejection fraction (EF) percentages along with cardiac output (CO) were measured through the right parasternal approach in papillary muscle level view. Moreover, the levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were measured by enzyme-linked immunosorbent assay before OHE (D0) as well as 10 (D10), 20 (D20) and 30 (D30) days after OHE. The results of this study showed that the mean FS and EF decreased on all days of the study. The FS reduction was significant between D10 and D30 and EF changes were significant between D10 and D20. The means of CO increased significantly on D0 compared to the D10. After D20, CO reduced until the end of the study. Mean concentrations of LH and FSH increased on all research days; but, the changes were significant until D20. Despite the negative effects of OHE on myocardial function, there was no significant correlation between hormonal levels and echocardiographic findings after OHE in this study.
卵巢子宫切除术（OHE）是兽医学中最常见的手术之一。尽管这种手术方法有几个优点，但它会改变心脏等各种器官的功能。本研究使用M型超声心动图研究了OHE对心脏功能的影响。共有10只健康的成年家养短毛猫参与了本研究。通过右胸骨旁途径在乳头肌水平视图中测量缩短分数（FS）、射血分数（EF）百分比以及心输出量（CO）。此外，在OHE前（D0）以及OHE后10天（D10）、20天（D20）和30天（D30）通过酶联免疫吸附测定法测量促黄体生成素（LH）和促卵泡激素（FSH）水平。本研究结果表明，在研究的所有天数中，平均FS和EF均下降。FS在D10和D30之间的降低具有显著性，EF在D10和D20之间的变化具有显著性。与D10相比，D0时CO平均值显著增加。D20后，CO一直降低直至研究结束。LH和FSH的平均浓度在所有研究天数中均升高；但是，这些变化在D20之前具有显著性。尽管OHE对心肌功能有负面影响，但在本研究中，OHE后激素水平与超声心动图结果之间没有显著相关性。
