Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India
Curr Stem Cell Res Ther. 2024;19(8):1072-1083. doi: 10.2174/011574888X268109230924233850.
This comprehensive review article examines the integration of biotechnology and stem cell therapy in breast cancer diagnosis and treatment. It discusses the use of biotechnological tools such as liquid biopsies, genomic profiling, and imaging technologies for accurate diagnosis and monitoring of treatment response. Stem cell-based approaches, their role in modeling breast cancer progression, and their potential for breast reconstruction post-mastectomy are explored. The review highlights the importance of personalized treatment strategies that combine biotechnological tools and stem cell therapies. Ethical considerations, challenges in clinical translation, and regulatory frameworks are also addressed. The article concludes by emphasizing the potential of integrating biotechnology and stem cell therapy to improve breast cancer outcomes, highlighting the need for continued research and collaboration in this field.
这篇综述文章探讨了生物技术和干细胞疗法在乳腺癌诊断和治疗中的整合。它讨论了使用生物技术工具，如液体活检、基因组分析和成像技术，进行准确的诊断和监测治疗反应。还探讨了基于干细胞的方法，它们在模拟乳腺癌进展中的作用，以及它们在乳房切除术后进行乳房重建的潜力。该综述强调了结合生物技术工具和干细胞疗法制定个性化治疗策略的重要性。还讨论了伦理考虑、临床转化的挑战和监管框架。文章最后强调了整合生物技术和干细胞疗法以改善乳腺癌预后的潜力，突出了在该领域继续进行研究和合作的必要性。
