Israel Center on Addiction, 2 HaTzoran Street, Netanya, Israel.
Lev Hasharon Medical Center, Netanya, Israel.
Subst Abuse Treat Prev Policy. 2023 Oct 12;18(1):58. doi: 10.1186/s13011-023-00566-7.
Substance use is a leading cause of preventable morbidity and mortality worldwide. Population-wide screening for problematic substance use in primary health care may mitigate the serious health and socio-economic consequences of such use, but the standard Alcohol, Smoking and Substance Involvement Screening Test (ASSIST 3.1) may be too long for wide-scale screening. How well validated shorter versions (ASSIST-Lite, ASSIST-FC) perform in identifying those with ASSIST 3.1 problematic use in different settings is unclear.
General population Jewish adults in Israel (N = 2,474) responded to an online survey that included the ASSIST 3.1 and sociodemographics. Across substances (alcohol, tobacco, cannabis, sedatives, prescription stimulants, prescription painkillers), receiver operator characteristic curve analysis determined that ASSIST-FC scores performed better than ASSIST-Lite at identifying those with problematic use, and evaluated differential ASSIST-FC performance by gender or age. Test characteristics and agreement were evaluated for binary ASSIST-FC versions, with ASSIST 3.1 problematic use as the gold standard.
ASSIST-FC scores showed high ability to identify ASSIST 3.1 problematic use, with minimal differences by gender or age. Binary ASSIST-FC (most substances: threshold 3+; alcohol: 5+) showed high specificity and positive predictive value, acceptable sensitivity, and good agreement.
The ASSIST-FC, which assesses frequency of use and other's concerns about use, appears useful for very brief screening in primary care to identify patients who may benefit from intervention. Early identification of those at-risk may prevent more severe consequences and ultimately decrease the significant costs of problematic substance use on the individual and population level.
物质使用是全球可预防发病率和死亡率的主要原因。在初级保健中对普遍人群进行物质使用问题筛查可能会减轻此类使用带来的严重健康和社会经济后果,但标准的酒精、吸烟和物质使用卷入筛查测试(ASSIST 3.1)可能太长,不适合大规模筛查。在不同环境中,较短版本(ASSIST-Lite、ASSIST-FC)在识别那些 ASSIST 3.1 物质使用问题方面的表现如何,尚不清楚。
以色列的普通人群犹太成年人(N=2474)对包括 ASSIST 3.1 和社会人口统计学在内的在线调查做出了回应。在各种物质(酒精、烟草、大麻、镇静剂、处方兴奋剂、处方止痛药)中,接收器操作特征曲线分析确定,ASSIST-FC 分数在识别有问题使用的人方面优于 ASSIST-Lite,并且评估了性别或年龄的差异 ASSIST-FC 表现。根据 ASSIST 3.1 物质使用问题作为金标准,评估了二进制 ASSIST-FC 版本的测试特征和一致性。
ASSIST-FC 分数显示出识别 ASSIST 3.1 物质使用问题的高能力,性别或年龄差异最小。二进制 ASSIST-FC(大多数物质:阈值 3+;酒精:5+)显示出高特异性和阳性预测值、可接受的敏感性和良好的一致性。
ASSIST-FC 评估使用频率和其他人对使用的关注,似乎非常适合在初级保健中进行非常简短的筛查,以识别可能受益于干预的患者。早期识别那些处于危险中的人可能会预防更严重的后果,并最终降低个人和人群层面上物质使用问题的巨大成本。