Almeida Vera, Pires Daniela, Silva Marta, Teixeira Maribel, Teixeira Ricardo João, Louro André, Dinis Maria Alzira Pimenta, Ferreira Maria, Teixeira Ana
UNIPRO-Oral Pathology and Rehabilition Research Unit, University Institute of Health Sciences (IUCS), CESPU, CRL, 4585-116 Gandra, Portugal.
UCIBIO-Applied Molecular Biosciences Unit, MedTech-Laboratory of Pharmaceutical Technology, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.
Healthcare (Basel). 2023 Sep 25;11(19):2621. doi: 10.3390/healthcare11192621.
Cancer is a leading cause of mortality and morbidity all over the world and the second major cause of death in Portugal. Dermatological side effects resulting from cancer treatment have a psychosocial impact on patients' lives, such as quality of life (QoL), body image, cognitive fusion and social inhibition. This systematic review aimed to explore and synthesize the psychosocial impact of dermatological side effects of cancer treatment, answering the following research objectives: (i) Do the dermatological side effects of the cancer treatment present any psychosocial impact for the patients? (ii) How does the psychosocial impact of the dermatological toxicities of the cancer treatment manifest in patients' lives? Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed and guided a systematic search through the PubMed, Cochrane Library and PyscNet databases. The considered studies correlate dermatological side effects of cancer treatments and their psychological/psychosocial outcomes. The studies found were all published in peer-reviewed journals. The results obtained established that cancer treatment causes the most varied skin changes, consequently reducing self-esteem and QoL; disturbing body image; and contributing to cases of stress, depression and anxiety. There is still limited literature that profoundly investigates the experience of living with these skin toxicities. The development of research lines to improve knowledge in this field will allow for significant improvements in healthcare for patients undergoing cancer treatment who need to focus more on the psychosocial implications of skin toxicities. The novelty of this review lies in adding knowledge summarizing the psychosocial implications of dermatological side effects of cancer treatment to support healthcare providers in the development of integrative therapeutic strategies for these patients in their clinical practice.
癌症是全球死亡和发病的主要原因之一，也是葡萄牙第二大主要死因。癌症治疗引起的皮肤副作用会对患者的生活产生社会心理影响，如生活质量（QoL）、身体形象、认知融合和社交抑制。本系统综述旨在探讨和综合癌症治疗皮肤副作用的社会心理影响，回答以下研究目标：（i）癌症治疗的皮肤副作用对患者是否存在任何社会心理影响？（ii）癌症治疗皮肤毒性的社会心理影响在患者生活中如何表现？遵循系统评价和Meta分析的首选报告项目（PRISMA）指南，并指导通过PubMed、Cochrane图书馆和PyscNet数据库进行系统检索。纳入的研究将癌症治疗的皮肤副作用与其心理/社会心理结果相关联。所发现的研究均发表在同行评审期刊上。获得的结果表明，癌症治疗会导致多种多样的皮肤变化，从而降低自尊和生活质量；扰乱身体形象；并导致压力、抑郁和焦虑等情况。深入研究这些皮肤毒性患者生活经历的文献仍然有限。开展研究以提高该领域的知识水平，将有助于显著改善接受癌症治疗患者的医疗保健，这些患者需要更多地关注皮肤毒性的社会心理影响。本综述的新颖之处在于增加了对癌症治疗皮肤副作用社会心理影响的知识总结，以支持医疗保健提供者在临床实践中为这些患者制定综合治疗策略。
