Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Clinic of Infectious diseases, Centre of Dermatovenereology, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Dermatology. 2020;236(4):314-322. doi: 10.1159/000506627. Epub 2020 Apr 6.
BACKGROUND/OBJECTIVE: Skin diseases, especially those with visible manifestation, are considered to cause a major influence on global mental health. Therefore, we determined the prevalence and severity of anxiety, depression, and suicidal ideation in a large sample of patients with facial dermatoses, namely acne, rosacea, folliculitis, and perioral dermatitis.
The mental health of patients with facial dermatoses and respective controls was assessed using the Hospital Anxiety and Depression Scale and questions concerning suicidal ideation.
The study included 543 patients with facial dermatoses and 497 healthy individuals. Anxiety was present in 37.6% of the patients (14.9% of controls), depression in 21.7% (6.8%), and suicidal thoughts in 9.8% (3.2%) (p < 0.001). Acne patients demonstrated the highest anxiety and depression subscale scores (mean ± standard deviation: 7.1 ± 0.25, 95% confidence interval (CI): 6.58-7.56; controls: 5 ± 0.23, 95% CI: 4.57-5.49). In rosacea 30% of the patients had depression symptoms (adjusted odds ratio (OR): 7.216, 95% CI: 4.122-12.632, p < 0.001), while in folliculitis patients 15.4% (OR: 3.138, 95% CI: 1.241-7.936, p = 0.016) had suicidal thoughts. Patients with anxiety symptoms and suicidal thoughts were on average younger than those without (28.3 ± 0.76 vs. 31.2 ± 0.66 years, p = 0.001 and 25.3 ± 0.98 vs. 30.5 ± 0.55 years, p = 0.007, respectively).
Acne and rosacea are associated with anxiety, depression, and suicidal ideation in Lithuanian patients. Younger patients are more prone to report such symptoms than older ones.
背景/目的:皮肤病,尤其是那些具有明显表现的皮肤病,被认为对全球心理健康有重大影响。因此,我们在大量患有面部皮肤病(即痤疮、酒渣鼻、毛囊炎和口周皮炎)的患者中确定了焦虑、抑郁和自杀意念的患病率和严重程度。
使用医院焦虑抑郁量表和自杀意念问题评估面部皮肤病患者和相应对照者的心理健康状况。
该研究纳入了 543 名面部皮肤病患者和 497 名健康个体。37.6%的患者存在焦虑(对照组为 14.9%),21.7%存在抑郁,9.8%存在自杀意念(p<0.001)。痤疮患者的焦虑和抑郁亚量表评分最高(平均值±标准偏差:7.1±0.25,95%置信区间(CI):6.58-7.56;对照组:5±0.23,95%CI:4.57-5.49)。在酒渣鼻患者中,30%有抑郁症状(调整后优势比(OR):7.216,95%CI:4.122-12.632,p<0.001),而在毛囊炎患者中,15.4%(OR:3.138,95%CI:1.241-7.936,p=0.016)有自杀意念。有焦虑症状和自杀意念的患者平均比没有的患者年轻(28.3±0.76 岁 vs. 31.2±0.66 岁,p=0.001 和 25.3±0.98 岁 vs. 30.5±0.55 岁,p=0.007)。
在立陶宛患者中,痤疮和酒渣鼻与焦虑、抑郁和自杀意念相关。年轻患者比年长患者更易报告这些症状。