Sirotiak Zoe, Thomas Emily B K, Brellenthin Angelique G
Iowa State University, Department of Kinesiology, USA.
University of Iowa, Department of Psychological and Brain Sciences, USA.
J Psychosom Res. 2023 Dec;175:111519. doi: 10.1016/j.jpsychores.2023.111519. Epub 2023 Oct 11.
Long COVID has been associated with psychological symptoms, yet it is unknown if the symptom burden of individuals with current and previous long COVID differ. This pre-registered cross-sectional study assessed stress, anxiety, and depression severity among individuals with no history, previous history, or current long COVID symptoms.
Adults (N = 2872) in the United States participated in an online survey detailing experiences related to the COVID-19 pandemic. Included participants reported ≥1 COVID-19 infection, and self-reported long COVID symptoms (past and present) were assessed. A multivariable linear regression evaluated the association of long COVID status and stress, anxiety, and depression severity. Post-hoc contrasts were performed to probe significant differences among no, previous, and current long COVID symptom groups.
Of 2872 participants with history of COVID-19 infection, 2310 reported no history of, 183 reported previous history of, and 379 reported current long COVID symptoms. Participants were an average 41.3 years of age, with most identifying as female (51.7%), White (87.7%), and non-Hispanic or Latino (84.1%). Individuals with current and previous history of long COVID reported greater stress, anxiety, and depression compared to the no history group (all ps < 0.05; current vs. no history Cohen's ds = 0.71-0.93; previous vs. no history ds = 0.30-0.66) after adjusting for demographic and lifestyle factors.
Both current and previous long COVID may be associated with psychological symptoms.
长期新冠与心理症状有关，但目前感染过新冠和既往感染过新冠的个体的症状负担是否存在差异尚不清楚。这项预先注册的横断面研究评估了无新冠病史、既往有新冠病史或目前有长期新冠症状的个体的压力、焦虑和抑郁严重程度。
美国的成年人（N = 2872）参与了一项在线调查，该调查详细描述了与新冠疫情相关的经历。纳入的参与者报告有≥1次新冠病毒感染，并对自我报告的长期新冠症状（过去和现在）进行了评估。多变量线性回归评估了长期新冠状态与压力、焦虑和抑郁严重程度之间的关联。进行事后对比以探究无、既往和目前有长期新冠症状组之间的显著差异。
在2872名有新冠病毒感染史的参与者中，2310人报告无新冠病史，183人报告既往有新冠病史，379人报告目前有长期新冠症状。参与者的平均年龄为41.3岁，大多数人认定为女性（51.7%）、白人（87.7%）、非西班牙裔或拉丁裔（84.1%）。在调整了人口统计学和生活方式因素后，目前和既往有长期新冠病史的个体与无新冠病史组相比，报告了更大的压力、焦虑和抑郁（所有p值<0.05；目前与无新冠病史组的科恩d值=0.71 - 0.93；既往与无新冠病史组的d值=0.30 - 0.66）。
目前和既往的长期新冠都可能与心理症状有关。
