College of Pharmacy, Ningxia Medical University, Yinchuan 750004, China.
Key Laboratory of Hui Ethnic Medicine Modernization of Ministry of Education, Ningxia Medical University, Yinchuan 750004, China.
Molecules. 2023 Oct 7;28(19):6966. doi: 10.3390/molecules28196966.
Licorice is a remarkable traditional Chinese medicine obtained from the dried root and rhizomes of the Glycyrrhiza genus, and t has been utilized in China for many centuries. It consists of more than 300 compounds that are mainly divided into triterpene saponins, flavonoids, polysaccharides, and phenolic components. The active compounds of licorice have been found to possess multiple biological activities, including antitumor, anti-inflammatory, antiviral, antimicrobial, immunoregulatory, cardioprotective, and neuroprotective functions. In addition to providing a brief overview of licorice's adjuvant properties, this review describes and analyzes the pharmacological mechanisms by which licorice components function to treat gastric cancer. Furthermore, licorice compounds are also found to be potent adjuvant chemotherapy agents, as they can improve the quality of life of cancer patients and alleviate chemotherapy-induced adverse effects.
甘草是一种源于甘草属植物的干燥根和根茎的中药，在中国已经使用了数百年。它由 300 多种化合物组成，主要分为三萜皂苷、黄酮类、多糖和酚类成分。甘草的活性化合物已被发现具有多种生物活性，包括抗肿瘤、抗炎、抗病毒、抗菌、免疫调节、心脏保护和神经保护功能。除了简要概述甘草的辅助特性外，本综述还描述和分析了甘草成分治疗胃癌的药理机制。此外，甘草化合物也被发现是有效的辅助化疗药物，因为它们可以提高癌症患者的生活质量并减轻化疗引起的不良反应。
