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甘草综述:制备、化学成分、生物活性及其应用

A Comprehensive Review of Licorice: The Preparation, Chemical Composition, Bioactivities and Its Applications.

作者信息

Ji Xiaoyu, Liu Ning, Huang Shucheng, Zhang Cai

机构信息

Henan International Joint Laboratory of Animal Welfare and Health Breeding, Henan University of Science and Technology, Luoyang 471023, P. R. China.

Henan Engineering Research Center of Livestock and Poultry, Emerging Disease Detection and Control, Luoyang 471023, P. R. China.

出版信息

Am J Chin Med. 2024;52(3):667-716. doi: 10.1142/S0192415X24500289. Epub 2024 May 8.

DOI:10.1142/S0192415X24500289
PMID:38716617
Abstract

Licorice () is a medicinal and food homologue of perennial plants derived from the dried roots and rhizomes of the genus in the legume family. In recent years, the comprehensive utilization of licorice resources has attracted people's attention. It is widely utilized to treat diseases, health food products, food production, and other industrial applications. Furthermore, numerous bioactive components of licorice are found using advanced extraction processes, which mainly include polyphenols (flavonoids, dihydrostilbenes, benzofurans, and coumarin), triterpenoids, polysaccharides, alkaloids, and volatile oils, all of which have been reported to possess a variety of pharmacological characteristics, including anti-oxidant, anti-inflammatory, antibacterial, antiviral, anticancer, neuroprotective, antidepressive, antidiabetic, antiparasitic, antisex hormone, skin effects, anticariogenic, antitussive, and expectorant activities. Thereby, all of these compounds promote the development of novel and more effective licorice-derived products. This paper reviews the progress of research on extraction techniques, chemical composition, bioactivities, and applications of licorice to provide a reference for further development and application of licorice in different areas.

摘要

甘草是一种多年生植物的药食同源物,来源于豆科甘草属植物的干燥根及根茎。近年来,甘草资源的综合利用受到人们的关注。它被广泛用于治疗疾病、保健食品、食品生产及其他工业应用。此外,利用先进的提取工艺发现了甘草的众多生物活性成分,主要包括多酚类(黄酮类、二氢茋类、苯并呋喃类和香豆素类)、三萜类、多糖类、生物碱类和挥发油类,据报道所有这些成分都具有多种药理特性,包括抗氧化、抗炎、抗菌、抗病毒、抗癌、神经保护、抗抑郁、抗糖尿病、抗寄生虫、抗性激素、皮肤效应、防龋、镇咳和祛痰活性。因此,所有这些化合物促进了新型且更有效的甘草衍生产品的开发。本文综述了甘草提取技术、化学成分、生物活性及应用的研究进展,为甘草在不同领域的进一步开发和应用提供参考。

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