Department of Neurology, Penn State University, Hershey Medical Center, Hershey, PA, USA.
Faculty of Medicine, Center for Tropical Diseases and Global Health (CTDGH), Université Catholique de Bukavu (UCB), Bukavu, Democratic Republic of Congo.
Curr Neurol Neurosci Rep. 2023 Nov;23(11):785-800. doi: 10.1007/s11910-023-01308-9. Epub 2023 Oct 14.
This review aims at providing updates on selected post-stroke complications. We examined recent advances in diagnosing and treating the following post-stroke complications: cognitive impairment, epilepsy, depression, fatigue, tremors, dysphagia, and pain.
Advances in understanding the mechanisms of post-stroke complications, in general, are needed despite advances made in understanding, treating, and preventing these complications. There are growing progresses in integrating new tools to diagnose post-stroke cognitive impairment. The potential role of acute stroke reperfusion treatment in post-stroke epilepsy and its impact on other stroke complications is getting more transparent. Post-stroke depression remains underestimated and new tools to diagnose depression after stroke are being developed. New promising pharmacological approaches to treating post-stroke pain are emerging. Tremors related to stroke are poorly understood and under-evaluated, while treatment towards post-stroke dysphagia has benefited from new non-pharmacological to pharmacological approaches.
An integrative approach to stroke complications and collaborations between providers across specialties are more likely to improve stroke outcomes.
本文旨在介绍部分脑卒中后并发症的最新研究进展。我们主要探讨了以下脑卒中后并发症的诊断和治疗新进展:认知障碍、癫痫、抑郁、疲劳、震颤、吞咽障碍和疼痛。
尽管在理解、治疗和预防这些并发症方面取得了进展,但仍需要深入了解脑卒中后并发症的发病机制。脑卒中后认知障碍的诊断工具也在不断改进,脑卒中后癫痫的急性再灌注治疗及其对其他脑卒中并发症的影响也越来越明晰。脑卒中后抑郁仍被低估,新的脑卒中后抑郁诊断工具正在研发中。治疗脑卒中后疼痛的新的有前景的药物治疗方法也在不断涌现。与脑卒中相关的震颤了解甚少,评估不足,而脑卒中后吞咽障碍的治疗则得益于新的非药物和药物治疗方法。
综合治疗脑卒中并发症,以及多学科医生间的合作,更有助于改善脑卒中患者的预后。