Department of Radiation Oncology, Seoul National University Hospital, Seoul 03080, Republic of Korea.
Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul 03080, Republic of Korea.
J Radiat Res. 2023 Nov 21;64(6):973-981. doi: 10.1093/jrr/rrad075.
The patient-specific bolus fabricated by a mold-and-cast method using a 3D printer (3DP) and silicon rubber has been adopted in clinical practices. Manufacturing a mold using 3DP, however, can cause time delays due to failures during the 3D printing process. Thereby, we investigated an alternative method of the mold fabrication using computer numerical control (CNC) machine tools. Treatment plans were conducted concerning a keloid scar formed on the ear and nose. The bolus structures were determined in a treatment planning system (TPS), and the molds were fabricated using the same structure file but with 3DP and CNC independently. Boluses were then manufactured using each mold with silicone rubbers. We compared the geometrical difference between the boluses and the planned structure using computed tomography (CT) images of the boluses. In addition, dosimetric differences between the two measurements using each bolus and the differences between the measured and calculated dose from TPS were evaluated using an anthropomorphic head phantom. Geometrically, the CT images of the boluses fabricated by the 3DP mold and the CNC mold showed differences compared to the planned structure within 2.6 mm of Hausdorff distance. The relative dose difference between the measurements using either bolus was within 2.3%. In conclusion, the bolus made by the CNC mold benefits from a stable fabricating process, retaining the performance of the bolus made by the 3DP mold.
使用 3D 打印机(3DP)和硅橡胶通过模压铸造方法制造的个体化射野内挡块已在临床实践中得到应用。然而,使用 3DP 制造模具会因 3D 打印过程中的故障而导致时间延迟。因此,我们研究了使用数控机床(CNC)制造模具的替代方法。针对耳朵和鼻子上形成的瘢痕疙瘩制定了治疗计划。在治疗计划系统(TPS)中确定了挡块结构,并使用相同的结构文件分别使用 3DP 和 CNC 独立制造模具。然后使用每个模具和硅橡胶制造挡块。我们使用挡块的 CT 图像比较了挡块和计划结构之间的几何差异。此外,还使用人体头部模型评估了使用每个挡块进行的两种测量之间的剂量差异以及 TPS 测量和计算剂量之间的差异。在几何形状方面,与计划结构相比,通过 3DP 模具和 CNC 模具制造的挡块的 CT 图像在 Hausdorff 距离 2.6mm 内存在差异。使用任一个挡块进行的测量之间的相对剂量差异在 2.3%以内。总之,CNC 模具制造的挡块具有稳定的制造工艺,保留了 3DP 模具制造的挡块的性能。