胃食管反流病患者近端和远端反流监测的临床特征分析
Analysis of clinical characteristics in proximal and distal reflux monitoring among patients with gastroesophageal reflux disease.
作者信息
Wang Ping, Yu Jie, Heng Bing-Lin, Chen Yan, Guo Hong, Zhang Ying-Jian
机构信息
School of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, Luoyang 471003, Henan, China.
Department of Gastroenterology, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang 471003, Henan, China.
出版信息
Open Med (Wars). 2023 Oct 11;18(1):20230791. doi: 10.1515/med-2023-0791. eCollection 2023.
The purpose of this study was to examine the characteristics of proximal and distal gastroesophageal reflux in patients with gastroesophageal reflux disorder and analyze their clinical symptoms. A total of 67 patients with typical esophageal symptoms were selected for this study. All participants completed the reflux disease questionnaire and a questionnaire survey of extraesophageal symptoms. Diagnosis was made using a 24-h impedance-pH detection and proton pump inhibitor. The results showed that the proximal reflux group had a higher number of acid reflux episodes compared to the distal reflux group ( < 0.05). Similarly, the proximal reflux group also had a higher number of gas reflux episodes compared to the distal reflux group ( < 0.05). On the other hand, the distal reflux group had a higher number of mixed reflux episodes compared to the proximal reflux group ( < 0.05). These differences were statistically significant. This study revealed that acid reflux and gas reflux were more predominant in the proximal reflux group, while mixed reflux was more predominant in the distal reflux group.
本研究的目的是检查胃食管反流病患者近端和远端胃食管反流的特征，并分析其临床症状。本研究共选取了67例有典型食管症状的患者。所有参与者均完成了反流疾病问卷和食管外症状问卷调查。采用24小时阻抗-pH检测和质子泵抑制剂进行诊断。结果显示，近端反流组的酸反流发作次数高于远端反流组（<0.05）。同样，近端反流组的气体反流发作次数也高于远端反流组（<0.05）。另一方面，远端反流组的混合反流发作次数高于近端反流组（<0.05）。这些差异具有统计学意义。本研究表明，酸反流和气体反流在近端反流组中更为突出，而混合反流在远端反流组中更为突出。
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