细胞内注射镧离子（La3+）和锰离子（Mn2+）对心脏细胞电偶联的影响。
Effect of intracellular injection of La3+ and Mn2+ on electrical coupling of heart cells.
作者信息
De Mello W C
出版信息
Cell Biol Int Rep. 1979 Mar;3(2):113-9. doi: 10.1016/0309-1651(79)90115-2.
The effect of intracellular injection of La3+ and Mn2+ on the electrical coupling of canine Purkinje cells investigated. It was found that La3+ causes cell decoupling in about 100 sec, increased the input resistance of the injected cell too. Mn2+ injection reduced drastically the coupling coefficient but did not abolish cell communication. Intracellular injection of La3+ or Mn2+ also caused shortening of the action potential and hyperpolarized the the heart cells. La3+ seems to be as effective as Ca or even stronger than Ca in suppressing intercellular communication in heart fibres.
研究了细胞内注射La3+和Mn2+对犬浦肯野细胞电偶联的影响。发现La3+在约100秒内导致细胞去偶联，同时也增加了被注射细胞的输入电阻。注射Mn2+显著降低了偶联系数，但并未消除细胞间通讯。细胞内注射La3+或Mn2+还导致动作电位缩短并使心脏细胞超极化。在抑制心脏纤维细胞间通讯方面，La3+似乎与Ca一样有效，甚至比Ca更强。
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