Academy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China.
Shandong Province Key Laboratory of Detection Technology for Tumor Makers, Medical College, Linyi University, Linyi, 276000, China.
Adv Mater. 2024 Jan;36(3):e2308726. doi: 10.1002/adma.202308726. Epub 2023 Nov 22.
Piezoelectric, pyroelectric, and ferroelectric materials are considered unique biomedical materials due to their dielectric crystals and asymmetric centers that allow them to directly convert various primary forms of energy in the environment, such as sunlight, mechanical energy, and thermal energy, into secondary energy, such as electricity and chemical energy. These materials possess exceptional energy conversion ability and excellent catalytic properties, which have led to their widespread usage within biomedical fields. Numerous biomedical applications have demonstrated great potential with these materials, including disease treatment, biosensors, and tissue engineering. For example, piezoelectric materials are used to stimulate cell growth in bone regeneration, while pyroelectric materials are applied in skin cancer detection and imaging. Ferroelectric materials have even found use in neural implants that record and stimulate electrical activity in the brain. This paper reviews the relationship between ferroelectric, piezoelectric, and pyroelectric effects and the fundamental principles of different catalytic reactions. It also highlights the preparation methods of these three materials and the significant progress made in their biomedical applications. The review concludes by presenting key challenges and future prospects for efficient catalysts based on piezoelectric, pyroelectric, and ferroelectric nanomaterials for biomedical applications.
压电、热释电和铁电材料被认为是独特的生物医学材料，因为它们的介电晶体和不对称中心允许它们直接将环境中的各种初级能源，如阳光、机械能和热能，转化为二次能源，如电能和化学能。这些材料具有卓越的能量转换能力和优异的催化性能，这使得它们在生物医学领域得到了广泛的应用。许多生物医学应用已经证明了这些材料具有巨大的潜力，包括疾病治疗、生物传感器和组织工程。例如，压电材料被用于刺激骨再生中的细胞生长，而热释电材料则应用于皮肤癌的检测和成像。铁电材料甚至在神经植入物中得到了应用，这些植入物可以记录和刺激大脑中的电活动。本文综述了铁电、压电和热释电效应之间的关系以及不同催化反应的基本原理。它还强调了这三种材料的制备方法以及它们在生物医学应用中的重要进展。本文最后提出了基于压电、热释电和铁电纳米材料的生物医学应用的高效催化剂的关键挑战和未来展望。
