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微生物学与死后间隔时间:系统综述。

Microbiology and postmortem interval: a systematic review.

机构信息

Departamento de Ciências da Saúde Pública e Forenses e Educação Médica, Faculdade de Medicina, Universidade do Porto, Porto, Portugal.

Faculdade de Medicina Dentária da Universidade do Porto, Porto, Portugal.

出版信息

Forensic Sci Med Pathol. 2024 Jun;20(2):696-715. doi: 10.1007/s12024-023-00733-z. Epub 2023 Oct 16.

Abstract

This systematic review aims to learn if and how it is possible to use the human microbiome to indicate the time elapsed after death. Articles were searched on the PubMed database using predefined data fields and keywords; reviews, systematic reviews, and meta-analyses were excluded. The final selection included 14 papers (out of 144). The results indicated that the microorganisms present in the cadaveric island succeed predictably over time, with markers between the stages of decomposition constituting a potential innovative tool for postmortem interval (PMI) estimation. The human microbiome has the potential to be used for PMI estimation and may present advantages as microbes are present in all seasons, in all habitats, including the most extreme ones, and because microbial communities respond predictably to environmental changes.

摘要

本系统评价旨在了解是否以及如何利用人类微生物组来指示死后经过的时间。使用预定义的数据字段和关键词在 PubMed 数据库中搜索文章;排除综述、系统评价和荟萃分析。最终选择包括 14 篇论文(共 144 篇)。结果表明,随着时间的推移,尸体岛上存在的微生物可以准确地预测,其中分解阶段之间的标志物构成了死后间隔(PMI)估计的潜在创新工具。人类微生物组有可能用于 PMI 估计,并且可能具有优势,因为微生物存在于所有季节、所有栖息地,包括最极端的栖息地,并且因为微生物群落对环境变化有可预测的反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96d1/11297127/77b20b822a32/12024_2023_733_Fig1_HTML.jpg

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