Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Best Pract Res Clin Gastroenterol. 2023 Oct;66:101839. doi: 10.1016/j.bpg.2023.101839. Epub 2023 May 23.
Colorectal Cancer (CRC) is the third most commonly diagnosed form of cancer and accounts for approximately 1.9 million cancer cases each year (10% of all new cancer cases globally). Incidence strongly increases with age and has been traditionally highest in Western, affluent countries, but it is rapidly increasing in many less developed countries and in younger generations in both developed and developing countries. With demographic aging, CRC will pose a rapidly increasing challenge for many societies, which underlines the need for major efforts on primary and secondary prevention. A number of effective screening options are available, and implementation of well-organized screening programs could have a major impact on lowering the future burden of the disease.
结直肠癌(CRC)是第三大常见癌症,每年约有 190 万例(占全球所有新发癌症病例的 10%)。发病率随着年龄的增长而强烈增加,传统上在西方富裕国家最高,但在许多欠发达国家以及发达国家和发展中国家的年轻一代中迅速增加。随着人口老龄化,CRC 将对许多社会构成迅速增加的挑战,这突显了在初级和二级预防方面做出重大努力的必要性。有许多有效的筛查选择,实施组织良好的筛查计划可能会对降低未来疾病负担产生重大影响。