Cao Zhan, Guo Mingjie, Cao Xun, Liu Tiantian, Hu Shaowen, Xiao Yafei, Zhang Min, Liu Hengfang
Department of Neurology, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Department of Thoracic and Cardiovascular Surgery, The First Affiliated Hospital of Henan University, Kaifeng, China.
Front Neurol. 2023 Oct 3;14:1223457. doi: 10.3389/fneur.2023.1223457. eCollection 2023.
Temporal lobe epilepsy (TLE) is the most common cause of drug-resistant epilepsy and can be treated surgically to control seizures. In this study, we analyzed the relevant research literature in the field of temporal lobe epilepsy (TLE) treatment to understand the background, hotspots, and trends in TLE treatment research.
We discussed the trend, frontier, and hotspot of scientific output in TLE treatment research in the world in the last 20 years by searching the core collection of the Web of Science database. Excel and CiteSpace software were used to analyze the basic data of the literature.
We identified a total of 2,051 publications on TLE treatment from 75 countries between 2003 and 2023. We found that the publication rate was generally increasing. The United States was the most publishing country; among the research institutions on TLE treatment, the University of California system published the most relevant literature and collaborated the most with other institutions. The co-citation of literature, keyword co-occurrence, and its clustering analysis showed that the early studies focused on open surgical treatment, mainly by lobectomy. In recent years, the attention given to stereotactic, microsurgery, and other surgical techniques has gradually increased, and the burst analysis indicated that new research hotspots may appear in the future in the areas of improved surgical procedures and mechanism research.
颞叶癫痫（TLE）是药物难治性癫痫最常见的病因，可通过手术治疗来控制癫痫发作。在本研究中，我们分析了颞叶癫痫（TLE）治疗领域的相关研究文献，以了解TLE治疗研究的背景、热点和趋势。
通过检索Web of Science数据库核心合集，探讨过去20年全球TLE治疗研究的科学产出趋势、前沿和热点。使用Excel和CiteSpace软件分析文献的基础数据。
我们共识别出2003年至2023年间来自75个国家的2051篇关于TLE治疗的出版物。我们发现发表率总体呈上升趋势。美国是发表量最多的国家；在TLE治疗的研究机构中，加利福尼亚大学系统发表的相关文献最多，且与其他机构的合作最为广泛。文献共被引、关键词共现及其聚类分析表明，早期研究集中在开放性手术治疗，主要是叶切除术。近年来，对立体定向、显微手术等手术技术的关注逐渐增加，突发分析表明未来在改进手术程序和机制研究领域可能会出现新的研究热点。
