The School of Precision Instrument and Opto-Electronics Engineering, Tianjin University, Nankai District, No.92 Weijin Road, Tianjin, China.
The Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Biomed Eng Online. 2023 Oct 19;22(1):101. doi: 10.1186/s12938-023-01163-2.
Myocardial bridges are congenital anatomical abnormalities in which myocardium covers a segment of coronary arteries, leading to stenocardia, myocardial ischemia, and sudden cardiac death in severe cases. However, automatic diagnosis of myocardial bridge presents significant challenges.
A novel framework of myocardial bridge detection with x-ray angiography sequence is proposed, which can realize automatic detection of vessel stenosis and myocardial bridge. Firstly, we employ a novel neural network model for coronary vessel segmentation, which consists of both CNNs and transformer structures to effectively extract both local and global information of the vessels. Secondly, we describe the vessel segment information, establish the vessel tree in the image, and fuse the vessel tree information between sequences. Finally, based on vessel stenosis detection, we realize automatic detection of the myocardial bridge by querying the blood vessels between the image sequence information.
In experiment, we evaluate the segmentation results using two metrics, Dice and ASD, and achieve scores of 0.917 and 1.39, respectively. In the stenosis detection, we achieve an average accuracy rate of 92.7% in stenosis detection among 262 stenoses. In multi-frame image processing, vessels in different frames can be well-matched, and the accuracy of myocardial bridge detection achieves 75%.
Our experimental results demonstrate that the algorithm can automatically detect stenosis and myocardial bridge, providing a new idea for subsequent automatic diagnosis of coronary vessels.
心肌桥是一种先天性解剖异常,心肌覆盖冠状动脉的一段,导致严重情况下出现心绞痛、心肌缺血和心脏性猝死。然而,心肌桥的自动诊断存在很大的挑战。
提出了一种基于 X 射线血管造影序列的心肌桥检测新框架,可实现血管狭窄和心肌桥的自动检测。首先,我们采用了一种新的冠状动脉分割神经网络模型,它结合了卷积神经网络和转换器结构,可有效提取血管的局部和全局信息。其次,我们描述了血管段信息,在图像中建立血管树,并融合序列之间的血管树信息。最后,基于血管狭窄检测,通过查询图像序列信息之间的血管,实现心肌桥的自动检测。
在实验中,我们使用两个度量标准(Dice 和 ASD)评估分割结果,分别获得 0.917 和 1.39 的分数。在狭窄检测中,在 262 个狭窄中,平均狭窄检测准确率达到 92.7%。在多帧图像处理中,不同帧中的血管可以很好地匹配,心肌桥检测的准确率达到 75%。
实验结果表明,该算法可以自动检测狭窄和心肌桥,为后续冠状动脉的自动诊断提供了新的思路。