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Advances in Blood-Brain Barrier Disruption to Facilitate Drug Delivery for Infiltrative Gliomas.

作者信息

Gould Andrew, Gonzales Victor Andrés Arrieta, Dmello Crismita Clement, Saganty Ruth, Lukas Rimas V, Zhang Daniel Y, Heimberger Amy B, Canney Michael, Carpentier Alexandre, Desseaux Carole, Bouchoux Guillaume, Stupp Roger, Sonabend Adam M

机构信息

Department of Neurosurgery, Northwestern University, Feinberg School of Medicine, Chicago Illinois.

Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago Illinois.

出版信息

Adv Oncol. 2023 May;3(1):77-86. doi: 10.1016/j.yao.2023.01.017. Epub 2023 Apr 7.

DOI:10.1016/j.yao.2023.01.017
PMID:37860079
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10583833/
Abstract
摘要

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Pilot study of repeated blood-brain barrier disruption in patients with mild Alzheimer's disease with an implantable ultrasound device.轻度阿尔茨海默病患者用植入式超声装置重复血脑屏障破坏的初步研究。
Alzheimers Res Ther. 2022 Mar 8;14(1):40. doi: 10.1186/s13195-022-00981-1.
2
MR-guided focused ultrasound enhances delivery of trastuzumab to Her2-positive brain metastases.MR 引导聚焦超声增强曲妥珠单抗向 Her2 阳性脑转移瘤的递送。
Sci Transl Med. 2021 Oct 13;13(615):eabj4011. doi: 10.1126/scitranslmed.abj4011.
3
Localized blood-brain barrier opening in infiltrating gliomas with MRI-guided acoustic emissions-controlled focused ultrasound.MRI 引导的声发射控制聚焦超声打开浸润性脑胶质瘤的局部血脑屏障。
Proc Natl Acad Sci U S A. 2021 Sep 14;118(37). doi: 10.1073/pnas.2103280118.
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Opening of the Blood-Brain Barrier Using Low-Intensity Pulsed Ultrasound Enhances Responses to Immunotherapy in Preclinical Glioma Models.采用低强度脉冲超声打开血脑屏障可增强临床前脑胶质瘤模型对免疫治疗的反应。
Clin Cancer Res. 2021 Aug 1;27(15):4325-4337. doi: 10.1158/1078-0432.CCR-20-3760. Epub 2021 May 24.
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Nat Commun. 2021 Feb 3;12(1):779. doi: 10.1038/s41467-021-21022-9.
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J Neurosurg. 2020 Jan 3;134(2):475-483. doi: 10.3171/2019.10.JNS192206. Print 2021 Feb 1.
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Clin Cancer Res. 2020 Jan 15;26(2):477-486. doi: 10.1158/1078-0432.CCR-19-2182. Epub 2019 Dec 12.
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Temporary blood-brain barrier disruption by low intensity pulsed ultrasound increases carboplatin delivery and efficacy in preclinical models of glioblastoma.低强度脉冲超声暂时破坏血脑屏障可增加卡铂在胶质母细胞瘤临床前模型中的递送和疗效。
J Neurooncol. 2019 Aug;144(1):33-41. doi: 10.1007/s11060-019-03204-0. Epub 2019 Jun 13.