Cao Yunyun, Li Yanliang, Xiang Xiaoqing, Liu Xiguang, Ma Guozhang
Heilongjiang Provincial Hospital, dermatology department, Harbin City, Heilongjiang Province, China.
Heilongjiang University of Chinese Medicine, Harbin City, Heilongjiang Province, China.
Photodiagnosis Photodyn Ther. 2023 Dec;44:103843. doi: 10.1016/j.pdpdt.2023.103843. Epub 2023 Oct 18.
Cutaneous squamous cell carcinoma (cSCC) is a prevalent malignant tumor typically treated through surgical removal. However, when the lesion is situated in specific areas like the hands, feet, or lips, particularly if it's sizable, surgical interventions can adversely impact appearance and function. In such cases, non-surgical treatments are preferable to preserve both aesthetics and functionality. We present a case of recurrent cSCC on the plantar region post-surgery. Given the extensive lesion area, deep infiltration, and the patient's reliance on foot function, hematoporphyrin derivative-photodynamic therapy (HpD-PDT) was chosen over traditional surgery. The lesion was successfully treated, and while a minor recurrence was observed after 20 months, it was localized and amenable to non-surgical intervention. We posit that HpD-PDT is a viable treatment for cSCC, especially in unique locations, with extensive lesions, and postoperative recurrence.
皮肤鳞状细胞癌（cSCC）是一种常见的恶性肿瘤，通常通过手术切除进行治疗。然而，当病变位于手部、足部或唇部等特定部位时，特别是如果病变较大，手术干预可能会对外观和功能产生不利影响。在这种情况下，非手术治疗更可取，以保持美观和功能。我们报告一例足底区域手术后复发性cSCC的病例。鉴于病变面积广泛、浸润较深且患者依赖足部功能，选择了血卟啉衍生物光动力疗法（HpD-PDT）而非传统手术。病变得到成功治疗，虽然20个月后观察到轻微复发，但复发部位局限且适合非手术干预。我们认为HpD-PDT是治疗cSCC的一种可行方法，特别是在独特部位、病变广泛以及术后复发的情况下。
