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一般人群中减少酒精使用的数字干预措施:一项更新的系统评价和荟萃分析。

Digital interventions for reducing alcohol use in general populations: An updated systematic review and meta-analysis.

作者信息

Sohi Ivneet, Shield Kevin D, Rehm Jürgen, Monteiro Maristela

机构信息

Centre for Addiction and Mental Health, Institute for Mental Health Policy Research, Toronto, Ontario, Canada.

Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.

出版信息

Alcohol Clin Exp Res (Hoboken). 2023 Oct;47(10):1813-1832. doi: 10.1111/acer.15175. Epub 2023 Oct 2.

DOI:10.1111/acer.15175
PMID:37864535
Abstract

This article updates a 2017 review on the effectiveness of digital interventions for reducing alcohol use in the general population. An updated systematic search of the MEDLINE database was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria to identify randomized controlled trials (RCTs) published from January 2017 to June 2022 that evaluated the effectiveness of digital interventions compared with no interventions, minimal interventions, and face-to-face interventions aimed at reducing alcohol use in the general population and, that also reported changes in alcohol use (quantity, frequency, quantity per drinking day, heavy episodic drinking (HED), or alcohol use disorders identification test (AUDIT) scores). A secondary analysis was performed that analyzed data from RCTs conducted in students. The review was not preregistered. The search produced 2224 articles. A total of 80 studies were included in the review, 35 of which were published after the last systematic review. A total of 66, 20, 18, 26, and 9 studies assessed the impact of digital interventions on alcohol quantity, frequency, quantity per drinking day, HED, and AUDIT scores, respectively. Individuals randomized to the digital interventions drank 4.12 (95% confidence interval (CI): 2.88, 5.36) fewer grams of alcohol per day, had 0.17 (95% CI 0.06, 0.29) fewer drinking days per week, drank approximately 3.89 (95% CI: 0.40, 7.38) fewer grams of alcohol per drinking day, had 1.11 (95% CI: 0.32, 1.91) fewer HED occasions per month, and had an AUDIT score 3.04 points lower (95% CI: 2.23, 3.85) than individuals randomized to the control condition. Significant reductions in alcohol quantity, frequency, and HED, but not quantity per drinking day, were observed among students. Digital interventions show potential for reducing alcohol use in general populations and could be used widely at the population level to reduce alcohol-attributable harms.

摘要

本文更新了2017年一篇关于数字干预措施对普通人群减少饮酒有效性的综述。按照系统评价和Meta分析的首选报告项目标准,对MEDLINE数据库进行了更新的系统检索,以识别2017年1月至2022年6月发表的随机对照试验(RCT),这些试验评估了数字干预措施与无干预措施、最小干预措施以及旨在减少普通人群饮酒的面对面干预措施相比的有效性,并且还报告了饮酒量(数量、频率、每日饮酒量、重度暴饮(HED)或酒精使用障碍识别测试(AUDIT)分数)的变化。进行了一项二次分析,分析了在学生中开展的RCT的数据。该综述未预先注册。检索共得到2224篇文章。该综述共纳入80项研究,其中35项是在上次系统评价之后发表的。分别有66项、20项、18项、26项和9项研究评估了数字干预措施对饮酒量、频率、每日饮酒量、HED和AUDIT分数的影响。随机接受数字干预措施的个体每天饮用的酒精量减少4.12克(95%置信区间(CI):2.88,5.36),每周饮酒天数减少0.17天(95%CI 0.06,0.29),每次饮酒日饮用的酒精量减少约3.89克(95%CI:0.40,7.38),每月HED次数减少1.11次(95%CI:0.32,1.91),AUDIT分数比随机分配到对照条件的个体低3.04分(95%CI:2.23,3.85)。在学生中观察到饮酒量、频率和HED有显著减少,但每日饮酒量没有减少。数字干预措施显示出在普通人群中减少饮酒的潜力,可在人群层面广泛应用以减少酒精所致危害。

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