Shu Jian-Jun, Tan Zi Hian, Wang Qi-Wen, Yong Kian-Yan
School of Mechanical & Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798.
J Am Chem Soc. 2023 Nov 22;145(46):25033-25042. doi: 10.1021/jacs.3c04142. Epub 2023 Oct 21.
Programmable biomolecule-mediated computing is a new computing paradigm as compared to contemporary electronic computing. It employs nucleic acids and analogous biomolecular structures as information-storing and -processing substrates to tackle computational problems. It is of great significance to investigate the various issues of programmable biomolecule-mediated processors that are capable of automatically processing, storing, and displaying information. This Perspective provides several conceptual designs of programmable biomolecule-mediated processors and provides some insights into potential future research directions for programmable biomolecule-mediated processors.
与当代电子计算相比，可编程生物分子介导的计算是一种新的计算范式。它采用核酸及类似的生物分子结构作为信息存储和处理的底物来解决计算问题。研究能够自动处理、存储和显示信息的可编程生物分子介导处理器的各种问题具有重要意义。本综述提供了可编程生物分子介导处理器的几种概念设计，并对可编程生物分子介导处理器未来潜在的研究方向提供了一些见解。
