Faculty of Chemistry, University of Science, HCM National University, Ho Chi Minh City, Vietnam.
Institute of Environment-Energy Technology, Sai Gon University, Ho Chi Minh City, Vietnam.
Nat Prod Res. 2024 Nov;38(22):3982-3988. doi: 10.1080/14786419.2023.2272024. Epub 2023 Oct 22.
One new prenyl flavanone (), (2)-8-prenyl-5,6-dihydroxy-7-methoxyflavanone, and one new diarylbutanol (), (7')-3'-hydroxy-linderagatin-A, were isolated from the stem bark of (Annonaceae), along with five known compounds, eriodictyol (), quercetin (), paprazine (), --caffeoyltyramine (), and --feruloyltyramine (). Their structures were determined through extensive spectroscopic analyses and comparison with the literature. The -glucosidase inhibitory potential of was evaluated. Compound showed the highest inhibitory activity against -glucosidase and exhibited superior potency compared to the positive control, with an IC value of 0.12 M.
从 （番荔枝科）的茎皮中分离得到了一种新的prenyl flavanone（），（2）-8-prenyl-5,6-dihydroxy-7-methoxyflavanone，和一种新的 diarylbutanol（），（7'）-3'-hydroxy-linderagatin-A，以及五种已知化合物，eriodictyol（），quercetin（），paprazine（），--caffeoyltyramine（），和--feruloyltyramine（）。通过广泛的光谱分析和与文献的比较确定了它们的结构。评估了 的 -葡萄糖苷酶抑制潜力。化合物 对 -葡萄糖苷酶表现出最高的抑制活性，其抑制活性优于阳性对照，IC 值为 0.12 M。
