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天然黄酮类化合物圣草酚的提取、生物合成、促进健康及治疗特性

The Extraction, Biosynthesis, Health-Promoting and Therapeutic Properties of Natural Flavanone Eriodictyol.

作者信息

Yin Haiaolong, Li Yaxian, Feng Yi, Tian Lei, Li Ye

机构信息

Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, China.

School of Medicine, Kunming University of Science and Technology, Kunming 650500, China.

出版信息

Nutrients. 2024 Dec 8;16(23):4237. doi: 10.3390/nu16234237.

DOI:10.3390/nu16234237
PMID:39683630
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11644446/
Abstract

Eriodictyol is a flavanone compound commonly found in several edible plants. Ultrasound-assisted extraction and high-performance liquid chromatography (HPLC) are commonly used methods for the separation and analysis of eriodictyol. Many studies show that some micro-organisms can produce eriodictyol as a host. What is more, eriodictyol has a wide range of health benefits, including skincare, neuroprotective, hypoglycemic, anti-inflammatory, and antioxidant activities. In addition, the therapeutic properties of eriodictyol are cardioprotective, hepatoprotective, anticancer, with protective effects on the lungs and kidneys, and so on. This review examines the extraction, biosynthesis, and health and therapeutic properties of the natural compound eriodictyol and its value in medicine and food.

摘要

圣草酚是一种常见于多种可食用植物中的黄烷酮化合物。超声辅助提取和高效液相色谱法(HPLC)是常用于分离和分析圣草酚的方法。许多研究表明,一些微生物能够作为宿主产生圣草酚。此外,圣草酚具有广泛的健康益处,包括护肤、神经保护、降血糖、抗炎和抗氧化活性。此外,圣草酚的治疗特性包括心脏保护、肝脏保护、抗癌以及对肺和肾脏的保护作用等。本文综述了天然化合物圣草酚的提取、生物合成、健康和治疗特性及其在医药和食品中的价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eb3/11644446/374813c42d65/nutrients-16-04237-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eb3/11644446/d3f8c134ef52/nutrients-16-04237-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eb3/11644446/374813c42d65/nutrients-16-04237-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eb3/11644446/d3f8c134ef52/nutrients-16-04237-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eb3/11644446/374813c42d65/nutrients-16-04237-g002.jpg

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The Extraction, Biosynthesis, Health-Promoting and Therapeutic Properties of Natural Flavanone Eriodictyol.天然黄酮类化合物圣草酚的提取、生物合成、促进健康及治疗特性
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Antiplatelet Effects of Flavonoid Aglycones Are Mediated by Activation of Cyclic Nucleotide-Dependent Protein Kinases.黄酮苷元的抗血小板作用是通过激活环核苷酸依赖的蛋白激酶介导的。
Int J Mol Sci. 2024 Apr 29;25(9):4864. doi: 10.3390/ijms25094864.
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Characterization of sodium alginate-carrageenan films prepared by adding peanut shell flavonoids as an antioxidant: Application in chilled pork preservation.
花生壳黄酮作为抗氧化剂制备的海藻酸钠-卡拉胶膜的特性:在冷却猪肉保鲜中的应用。
Int J Biol Macromol. 2024 May;266(Pt 1):131081. doi: 10.1016/j.ijbiomac.2024.131081. Epub 2024 Mar 27.
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Eriodictyol attenuates doxorubicin-induced nephropathy by activating the AMPK/Nrf2 signalling pathway.圣草酚通过激活AMPK/Nrf2信号通路减轻阿霉素诱导的肾病。
J Tradit Complement Med. 2023 Nov 8;14(2):203-214. doi: 10.1016/j.jtcme.2023.11.003. eCollection 2024 Mar.
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Artemisia argyi extracts overcome lapatinib resistance via enhancing TMPRSS2 activation in HER2-positive breast cancer.艾草提取物通过增强 HER2 阳性乳腺癌中的 TMPRSS2 激活来克服拉帕替尼耐药性。
Environ Toxicol. 2024 Jun;39(6):3389-3399. doi: 10.1002/tox.24202. Epub 2024 Mar 6.
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Eriodictyol inhibits the motility, angiogenesis and tumor growth of hepatocellular carcinoma via NLRP3 inflammasome inactivation.圣草酚通过抑制NLRP3炎性小体来抑制肝细胞癌的迁移、血管生成和肿瘤生长。
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