Department of Biochemistry, Auckland Park Kingsway Campus, University of Johannesburg, South Africa.
Department of Biotechnology and Food Technology, PO Box 17011, Doornfontein Campus, University of Johannesburg, South Africa.
Food Chem. 2024 Mar 15;436:137775. doi: 10.1016/j.foodchem.2023.137775. Epub 2023 Oct 15.
Aflatoxins (AFs) are toxic secondary metabolites prevalent in various food and agricultural products, posing significant challenges to global food safety. The detection and quantification of AFs through high-precision analytical techniques are crucial in mitigating AF contamination levels and associated health risks. Variousmethods,including conventional and emerging techniques, have been developed for detecting and quantifyingAFsinfood samples. This review provides an in-depth analysis of the global occurrence of AF in food commodities, covering their biosynthesis, mode of action, and effects on humans and animals. Additionally, the review discusses different conventional strategies, including chromatographic and immunochemical approaches, for AF quantification and identification in food samples. Furthermore, emerging AF detection strategies, such as solid-state gas sensors and electronic nose technologies, along with their applications, limitations, and future perspectives, were reviewed. Sample purification, along with their respective advantages and limitations, are also discussed herein.
黄曲霉毒素（AFs）是存在于各种食品和农产品中的有毒次生代谢物，对全球食品安全构成重大挑战。通过高精度分析技术检测和定量 AFs 对于降低 AF 污染水平和相关健康风险至关重要。已经开发了各种方法，包括传统和新兴技术，用于检测和定量食品样品中的 AF。本综述深入分析了食品商品中 AF 的全球发生情况，涵盖了它们的生物合成、作用模式以及对人类和动物的影响。此外，还讨论了不同的传统策略，包括色谱和免疫化学方法，用于食品样品中 AF 的定量和鉴定。此外，还回顾了新兴的 AF 检测策略，例如固态气体传感器和电子鼻技术，以及它们的应用、局限性和未来展望。本文还讨论了样品净化及其各自的优点和局限性。
