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整合代谢组学实现家禽精准营养:优化生长、饲料效率和健康状况

Integrating metabolomics for precision nutrition in poultry: optimizing growth, feed efficiency, and health.

作者信息

Abd El-Hack Mohamed E, Allam Ahmed A, Aldhalmi Ahmed K, Kamal Mahmoud, Arif Muhammad, Alawam Abdullah S, Rudayni Hassan A, Taha Ayman E, Swelum Ayman A, Elolimy Ahmed A, Madkour Mahmoud, Ashour Elwy A

机构信息

Department of Industrial Pharmacy, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology (MUST), Giza, Egypt.

Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.

出版信息

Front Vet Sci. 2025 May 22;12:1594749. doi: 10.3389/fvets.2025.1594749. eCollection 2025.

Abstract

Nutrition is an important factor in poultry production. This review highlights how precision nutrition improves poultry performance through metabolomics, which is a multidisciplinary approach that integrates traditional nutrition with other fields, including biology, immunology, molecular biology, genetics, computer sciences, chemistry, biochemistry, mathematics, engineering, and technology sciences. For measuring the results of the body's biochemical activities and figuring out Living systems' dynamic, multi-parametric metabolic response to pathological stimuli, metabolomics can be a very useful instrument. Numerous metabolomics techniques exist, including emerging capillary electrophoresis (CE), gas chromatography mass spectrometry (GC-MS), nuclear magnetic resonance spectroscopy (NMR), liquid chromatography mass spectrometry (LC-MS), inductively coupled plasma mass spectrometry (ICP-MS), and some targeted HPLC-based assays. Metabolomics can help in understanding the metabolism of diets (protein, carbohydrate, and fat) and the pathways of precise nutrition. Metabolomics can revolutionize poultry nutrition strategies, optimizing health, growth performance, and metabolic efficiency by decoding biochemical interactions between diet, metabolism, and physiology. This review aims to highlight methodologies for integrating metabolomic data into precision feeding systems, ultimately enhancing sustainability, reducing production costs, and improving poultry welfare.

摘要

营养是家禽生产中的一个重要因素。本综述强调了精准营养如何通过代谢组学提高家禽生产性能,代谢组学是一种多学科方法,将传统营养学与其他领域相结合,包括生物学、免疫学、分子生物学、遗传学、计算机科学、化学、生物化学、数学、工程学和技术科学。对于测量机体生化活动的结果以及弄清楚生命系统对病理刺激的动态、多参数代谢反应而言,代谢组学可能是一种非常有用的工具。存在多种代谢组学技术,包括新兴的毛细管电泳(CE)、气相色谱-质谱联用(GC-MS)、核磁共振波谱(NMR)、液相色谱-质谱联用(LC-MS)、电感耦合等离子体质谱(ICP-MS)以及一些基于高效液相色谱的靶向分析方法。代谢组学有助于理解日粮(蛋白质、碳水化合物和脂肪)的代谢以及精准营养的途径。代谢组学能够彻底改变家禽营养策略,通过解读日粮、代谢和生理学之间的生化相互作用来优化健康状况、生长性能和代谢效率。本综述旨在强调将代谢组学数据整合到精准饲喂系统中的方法,最终提高可持续性、降低生产成本并改善家禽福利。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bfda/12137320/94e8cae59634/fvets-12-1594749-g001.jpg

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