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一例原发性肝脏胃肠道间质瘤

A case of primary gastrointestinal stromal tumor of the liver.

作者信息

Nguyen Thi My Xuan An, Le Thi Bich Van, Le Van Dung, Bui Van Pham, Nguyen Tri Thuc, Le Van Phuoc

机构信息

Department of Radiology, Cho Ray Hospital, Ho Chi Minh, Viet Nam.

出版信息

Radiol Case Rep. 2023 Oct 17;18(12):4533-4536. doi: 10.1016/j.radcr.2023.08.108. eCollection 2023 Dec.

DOI:10.1016/j.radcr.2023.08.108
PMID:37868012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10587670/
Abstract

A gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. The tumor originates from Cajal cells, which generated peristaltic motion. Primary gastrointestinal stromal tumor of the liver is rare and should be considered in imaging diagnosis. We report a case of an 82-year-old female patient who represented with upper abdominal pain and poor appetite. Magnetic resonance imaging detected a large left lobe cystic lesion (10 × 15 cm). The tumor was resected. The histopathological and immunohistochemical results were of a primary gastrointestinal stromal tumor in the liver with cystic changes. On imaging, it is difficult to differentiate from other cystic lesions.

摘要

胃肠道间质瘤(GIST)是胃肠道最常见的间叶组织肿瘤。该肿瘤起源于产生蠕动的 Cajal 细胞。原发性肝脏胃肠道间质瘤罕见,在影像诊断中应予以考虑。我们报告一例 82 岁女性患者,表现为上腹部疼痛和食欲不佳。磁共振成像检测到左叶有一个大的囊性病变(10×15 厘米)。肿瘤被切除。组织病理学和免疫组化结果显示为肝脏原发性胃肠道间质瘤伴囊性变。在影像学上,它很难与其他囊性病变相鉴别。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c0/10587670/f177682c98b6/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c0/10587670/c0996e1feff0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c0/10587670/38ac84a3802a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c0/10587670/f177682c98b6/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c0/10587670/c0996e1feff0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c0/10587670/38ac84a3802a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2c0/10587670/f177682c98b6/gr3.jpg

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本文引用的文献

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Giant hepatic extra-gastrointestinal stromal tumor treated with cytoreductive surgery and adjuvant systemic therapy: A case report and review of literature.采用减瘤手术和辅助全身治疗的巨大肝脏胃肠外间质瘤:病例报告及文献复习
World J Gastrointest Surg. 2021 Mar 27;13(3):315-322. doi: 10.4240/wjgs.v13.i3.315.
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Clinicopathologic and immunohistochemical characteristics of upper gastrointestinal leiomyomas harboring interstitial cells of Cajal: A potential mimicker of gastrointestinal stromal tumor.胃上部胃肠道间质瘤的临床病理和免疫组织化学特征:胃肠道间质瘤的潜在模拟物。
Ann Diagn Pathol. 2020 Apr;45:151476. doi: 10.1016/j.anndiagpath.2020.151476. Epub 2020 Feb 5.
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Gastrointestinal stromal tumor: epidemiology, diagnosis, and treatment.
胃肠道间质瘤:流行病学、诊断与治疗。
Curr Opin Gastroenterol. 2019 Nov;35(6):555-559. doi: 10.1097/MOG.0000000000000584.
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Primary hepatic gastrointestinal stromal tumor with right adrenal gland invasion: A case report and systematic literature review.原发性肝胃肠间质瘤伴右肾上腺侵犯:一例报告及系统文献综述
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Giant gastrointestinal stromal tumor with predominantly cystic changes: a case report and literature review.以囊性改变为主的巨大胃肠道间质瘤:一例报告并文献复习。
World J Surg Oncol. 2017 Dec 13;15(1):220. doi: 10.1186/s12957-017-1285-2.
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Gastrointestinal stromal tumors (GIST) presenting in the liver: Diagnostic, prognostic and therapeutic issues.肝脏中出现的胃肠道间质瘤(GIST):诊断、预后及治疗问题
Clin Res Hepatol Gastroenterol. 2018 Apr;42(2):e23-e28. doi: 10.1016/j.clinre.2017.05.010. Epub 2017 Jun 20.
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Clinicopathological feature and prognosis of primary hepatic gastrointestinal stromal tumor.原发性肝脏胃肠道间质瘤的临床病理特征及预后
Cancer Med. 2016 Sep;5(9):2268-75. doi: 10.1002/cam4.808. Epub 2016 Aug 3.
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Coexisting and possible primary extra-gastrointestinal stromal tumors of the pancreas and liver: A single case report.胰腺和肝脏并存的及可能的原发性胃肠道外间质瘤:一例报告
Oncol Lett. 2016 May;11(5):3303-3307. doi: 10.3892/ol.2016.4420. Epub 2016 Apr 7.
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Rom J Morphol Embryol. 2014;55(2):291-6.
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Extrahepatic and intrahepatic human portal interstitial Cajal cells.肝外和肝内的人门脉间质 Cajal 细胞。
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